Results 41 to 50 of about 87,198 (136)

Modeling DNA Methylation Profiles and Epigenetic Analysis of Safflower (Carthamus tinctorius L.) Seedlings Exposed to Copper Heavy Metal

Toxics, 2023
Heavy metals are chemical elements with high density that can be toxic or poisonous even at low concentrations. They are widely distributed in the environment due to industrial activities, mining, pesticide use, automotive emissions and domestic wastes ...
Ekrem Bölükbaşı, Mehmet Karakaş
doaj   +1 more source

Crystal structure of yeast DNA polymerase ε catalytic domain. [PDF]

PLoS ONE, 2014
DNA polymerase ε (Polε) is a multi-subunit polymerase that contributes to genomic stability via its roles in leading strand replication and the repair of damaged DNA.
Rinku Jain, Kanagalaghatta R Rajashankar, Angeliki Buku, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal   +6 more
doaj   +1 more source

Mechanism for priming DNA synthesis by yeast DNA Polymerase α

eLife, 2013
The DNA Polymerase α (Pol α)/primase complex initiates DNA synthesis in eukaryotic replication. In the complex, Pol α and primase cooperate in the production of RNA-DNA oligonucleotides that prime synthesis of new DNA.
Rajika L Perera, Rubben Torella, Sebastian Klinge, Mairi L Kilkenny, Joseph D Maman, Luca Pellegrini   +5 more
doaj   +1 more source

Drought-Induced genomic and epigenetic variations in Quinoa genotypes revealed by iPBS and CRED-iPBS marker systems

Scientific Reports
Drought stress significantly impacts crop productivity, yet its influence on genomic and epigenetic variation in quinoa remains poorly understood.
Aras Türkoğlu, Kamil Haliloğlu, Fatih Demirel, Serap Demirel, Muhammet İslam Işık, Adnan Aydin, Mustafa Tan, Hadi Alipour   +7 more
doaj   +1 more source

Detection of Genetic Variations in Marine Algae Ulva lactuca (Chlorophyta) Induced by Heavy Metal Pollutants [PDF]

Journal of Stress Physiology & Biochemistry, 2015
Ulva lactuca (Chlorophyta) green macroalgae has been successfully used as bioindicator for heavy metals pollution in ecosystems. Random amplified microsatellite polymorphism (RAMP) marker was employed to investigate genetic DNA pattern variability in ...
Basel Saleh
doaj  

Nonradioactive Labeling of Large DNA Fragments for Genome Walking, RFLP and Northern Blot Analysis

BioTechniques, 1999
In this report, we present a simple nonradioactive labeling procedure for DNA fragments of high specific labeling density that can be used for a variety of applications.
Farzaneh Adhami, Sabine Müller, Marie-Theres Hauser   +2 more
doaj   +1 more source

RAD52 resolves transcription-replication conflicts to mitigate R-loop induced genome instability

Nature Communications
Collisions of the transcription and replication machineries on the same DNA strand can pose a significant threat to genomic stability. These collisions occur in part due to the formation of RNA-DNA hybrids termed R-loops, in which a newly transcribed RNA
Manisha Jalan, Aman Sharma, Xin Pei, Nils Weinhold, Erika S. Buechelmaier, Yingjie Zhu, Sana Ahmed-Seghir, Abhirami Ratnakumar, Melody Di Bona, Niamh McDermott, Joan Gomez-Aguilar, Kyrie S. Anderson, Charlotte K. Y. Ng, Pier Selenica, Samuel F. Bakhoum, Jorge S. Reis-Filho, Nadeem Riaz, Simon N. Powell   +17 more
doaj   +1 more source

The role of exogenous glutamine on germination, plant development and transcriptional expression of some stress-related genes in onion under salt stress

Folia Horticulturae
The purpose of this research was to explore the role of glutamine (Gln) on plant germination and growth under salinity [0, 50, 100, 150, 200 mM sodium chloride (NaCl)], and on the activation of some stress-related genes [CuZn-Superoxide Dismutase (SOD ...
Ulukapi Kamile, Nasircilar Ayse Gul
doaj   +1 more source

Structural basis for fork reversal and RAD51 regulation by the SCF ubiquitin ligase complex of F-box helicase 1

Nature Communications
Replication fork reversal helps maintain genomic stability during replication stress. F-box helicase 1 (FBH1) catalyzes fork reversal and is an SCF (SKP-CUL1-F-box) E3 ubiquitin ligase that limits RAD51 association with chromatin.
Briana H. Greer, Javier Mendia-Garcia, Elwood A. Mullins, Emma M. Peacock, Sander K. Haigh, Carl J. Schiltz, Clara Aicart-Ramos, Miaw-Sheue Tsai, David Cortez, Fernando Moreno-Herrero, Brandt F. Eichman   +10 more
doaj   +1 more source

Analyses of somaclonal variation in endosperm-supported mature embryo culture of rye (Secale cereale L.)

Biotechnology & Biotechnological Equipment, 2016
Genetic variations, and especially somaclonal variations, are undesirable in genetic transformation. In this study, random amplified polymorphic DNA (RAPD) and coupled restriction enzyme digestion-random amplification (CRED-RA) markers were used for ...
Murat Aydin, Esra Arslan, Mahmut Sinan Taspinar, Gokce Karadayi, Guleray Agar   +4 more
doaj   +1 more source