Results 131 to 140 of about 833,584 (297)

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

A novel and rapid method to generate single stranded DNA probes for genomic footprinting [PDF]

, 1988
Falk Weih, A. Francis Stewart, Günther Shütz   +2 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Paternal inheritance of egg traits in mice: a case of genomic imprinting [PDF]

, 1989
S. A. A. Bander, Shera Watson, J. G. M. Shire   +2 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Analysis of the genomic termini of tupaia herpesvirus DNA by restriction mapping and nucleotide sequencing [PDF]

, 1985
Marcus W. Albrecht, G. Darai, Rolf M. Flügel   +2 more
openalex   +1 more source

A genome conserved and a genome expanded [PDF]

Nature Reviews Genetics, 2014
openaire   +3 more sources

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

Unlocking the African bioeconomy and strengthening biodiversity conservation through genomics and bioinformatics

npj Biodiversity
The African BioGenome Project (AfricaBP) is a Pan-African initiative aimed at improving food systems and biodiversity conservation through genomics while ensuring equitable data sharing and benefits.
Ichrak Hayah, Victor Ezebuiro, Samuel Paul Kagame, Josiah Ochieng Kuja, Cecilia Waruhiu, Lucky Tendani Nesengani, Sinebongo Mdyogolo, Annelin Henriehetta Molotsi, Priscilla Abechi, Asmaa Mohamed Abushady, Nabil Amor, Brian Andika, Abdelhamid Barakat, Girish Beedessee, Marietjie Botes, Xavier David, Nzube Ebuzoeme, Zewdu Edea, Achraf El Allali, Owanate Pearl Elekima, Assem Kadry Elsherif, Semir Bechir Suheil Gaouar, Yohannes Gedamu Gebre, Owunari Abraham Georgewill, Lydia Hadjeras, Mohammed Ahmed Hassan, Mohamed Hijri, Isidore Houaga, Justin Eze Ideozu, Matthias Igoh, Mary Paschal Iwundu, Syed Arif Sulthan Jaffer Ali, Atef Jaouani, Ahmed Marwane Kermouni Serradj, Radjaa Khedim, Mariëtte Kilian, Dennis Manthi Kivuva, Mehdi Knidiri, Komi Komi Koukoura, Eleojo Roseline Kwasi, Kim Labuschagne, Antoine Lusala Mafwila, Isabel Mensah, Uzoma Modebelu, Prudent Mokgokong, Morad M. Mokhtar, Sadik Muzemil, Helen Nigussie, Valentine Otang Ntui, Joel Ogwang, Nicholas Abraham Olivier, Olanrewaju Olufowobi, Taiwo Crossby Omotoriogun, Onikepe Folarin, Philomena Eromon, Jeremiah Orina, Faissal Ouardi, Tracy Parish, Mercy Peter, Jacques Potgieter, Fouzia Radouani, Madeleine Ramantswana, Shaimaa Roshdy Abdullah Reda, Samson Pandam Salifu, Sarah Bingaman Schwartz, Ntji Shabangu, Abdoallah Sharaf, Iyeopu Minakiri Siminialayi, Rae Marvin Smith, Hiroaki Taniguchi, Preye Maureen Tari-Ukuta, Kassahun Tesfaye, Fatim Zohra Tmimi, Libert Brice Tonfack, Ogbuagu Ugorji Udensi, Victoria Wavinya Wambua, Sammy Wambua, Kennedy Were, Timipanipiri ThankGod Wood, Bret Mark Wurdeman, Yedomon Ange Bovys Zoclanclounon, Andrews Frimpong Adu, Sotonye Leslie Gillis-Harry, Nicholas Kwasi-Do Ohene Opoku, Thendo Stanley Tshilate, Siyeofori Dede, Soala Obie Minimah, Yves Hermandez Tchiechoua, Andreas Gisel, Chadlia Hamdi, Tshepo Mafokwane, Blessing Adanta Odogwu, Gift Nwachukwu, Zahra Mungloo-Dilmohamud, Faten Ghodhbane-Gtari, Chinagorom Ibeachu, Renate Dorothea Zipfel, Wenceslaus C. Madu, Johnpaul Chukwudi Okorocha, Tracy Masebe, Kilsi Borgbara, Wynand Goosen, Suereta Fortuin, Kristien Nel Van Zyl, Ongeziwe Mbhele, Anise Happi, Christian Happi, Ntanganedzeni Mapholi, Julian Onyewuonyeoma Osuji, Anne WT Muigai, ThankGod Echezona Ebenezer, Bouabid Badaoui   +111 more
doaj   +1 more source

Genomes within genomes [PDF]

Nature, 2007
openaire   +2 more sources