Results 21 to 30 of about 676,403 (246)
Genomics Portals: integrative web-platform for mining genomics data
BMC Genomics, 2010 Background A large amount of experimental data generated by modern high-throughput technologies is available through various public repositories. Our knowledge about molecular interaction networks, functional biological pathways and transcriptional ...
Ghosh Krishnendu +9 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson +20 more
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HRB Open Research, 2020 Genomics is revolutionizing biomedical research, medicine and healthcare globally in academic, public and industry sectors alike. Concrete examples around the world show that huge benefits for patients, society and economy can be accrued through ...
Cathal Seoighe +17 more
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Trends in : a statistical review of publications from 2003 to 2018 focusing on the most-studied genes and document clusters [PDF]
Genomics & Informatics, 2019 Genomics & Informatics (NLM title abbreviation: Genomics Inform) is the official journal of the Korea Genome Organization. Herein, we conduct a statistical analysis of the publications of Genomics & Informatics over the 16 years since its inception, with
Ji-Hyeon Kim, Hee-Jo Nam, Hyun-Seok Park
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Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez +14 more
wiley +1 more source
A genomics learning framework for undergraduates.
PLoS ONEGenomics is an increasingly important part of biology research. However, educating undergraduates in genomics is not yet a standard part of life sciences curricula.
Laura K Reed +8 more
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Frontiers in Public HealthIntroductionPathogen genomics, where whole genome sequencing technologies are used to produce complete genomic sequences of pathogens, is being increasingly used for infectious disease surveillance and outbreak response. Although proof-of-concept studies
James D. H. Ong +8 more
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Combinations of genes at the 16p11.2 and 22q11.2 CNVs contribute to neurobehavioral traits.
PLoS Genetics, 2023 The 16p11.2 and 22q11.2 copy number variants (CNVs) are associated with neurobehavioral traits including autism spectrum disorder (ASD), schizophrenia, bipolar disorder, obesity, and intellectual disability.
Mikhail Vysotskiy +4 more
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Frontiers in Genetics, 2018 Genomics and bioinformatics are increasingly contributing to our understanding of infectious diseases caused by bacterial pathogens such as Mycobacterium tuberculosis and parasites such as Plasmodium falciparum. This ranges from investigations of disease
Saikou Y. Bah +5 more
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
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