Results 81 to 90 of about 2,130,247 (378)

Toward an open access genomics database of South Africans: ethical considerations

Frontiers in Genetics, 2023
Genomics research holds the potential to improve healthcare. Yet, a very low percentage of the genomic data used in genomics research internationally relates to persons of African origin. Establishing a large-scale, open access genomics database of South
Amy Gooden, Donrich Thaldar, Donrich Thaldar   +2 more
doaj   +1 more source

(Re)-conciliation of genetics and genomics approaches for cotton fiber quality improvement [PDF]

, 2008
The integration of genomics and plant breeding is driven by the increasing availability of sequence resources and by technological developments. The simultaneous measurement of the expression of thousands of genes is possible, and comparisons between ...
Al-Ghazi, Yves, Arioli, Tony, Claverie, Michel, Dennis, Elizabeth, Derycker, Ruud, Forestier-Chiron, Nelly, Giband, Marc, Jacobs, John, Jean, Janine, Lacape, Jean-Marc, Llewellyn, Danny, Viot, Christopher   +11 more
core  

Autism genetics: searching for specificity and convergence. [PDF]

, 2012
Advances in genetics and genomics have improved our understanding of autism spectrum disorders. As many genes have been implicated, we look to points of convergence among these genes across biological systems to better understand and treat these ...
Berg, Jamee M, Geschwind, Daniel H
core   +1 more source

Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance [PDF]

, 2022
Patrick Munk, Christian Brinch, Frederik Duus Møller, Thomas Nordahl Petersen, René S. Hendriksen, Anne Mette Seyfarth, Jette Sejer Kjeldgaard, Christina Aaby Svendsen, Bram van Bunnik, Fanny Berglund, Artan Bego, P.P. Power, Catherine A. Rees, Dionisia Lambrinidis, Elizabeth Heather Jakobsen Neilson, Karen Gibb, Kris Coventry, Peter Collignon, Susan Cassar, Franz Allerberger, Anowara Begum, Zenat Zebin Hossain, Carlon Worrell, Olivier Vandenberg, Ilse Y. Pieters, Victorien Dougnon, Angela Daniela Salazar Gutierrez, Freddy Soria, Vesna Rudić Grujić, Nataša Mazalica, Teddie O. Rahube, Carlos Alberto Tagliati, Dália dos Prazeres Rodrigues, Guilherme Oliveira, Larissa Camila Ribeiro de Souza, Ivan Ivanov, Bonkoungou Isidore Juste, Traoré Soumana Oumar, Thet Sopheak, Yith Vuthy, Antoinette Ngandjio, Ariane Nzouankeu, Ziem A. Abah Jacques Olivier, Christopher K. Yost, Pratik Kumar, Satinder Kaur Brar, Djim-Adjim Tabo, Aiko D. Adell, Esteban Paredes-Osses, Maria Cristina Martinez, Sara Cuadros-Orellana, Changwen Ke, Huanying Zheng, Li Baisheng, Lok Ting Lau, Teresa Chung, Xiaoyang Jiao, Yongjie Yu, Zhao JiaYong, Johan F. Bernal Morales, María Fernanda Valencia, Pilar Donado-Godoy, Kalpy Julien Coulibaly, Jasna Hrenović, Matijana Jergović, Renáta Karpíšková, Zozo Nyarukweba Deogratias, Bodil Elsborg, Lisbeth Truelstrup Hansen, Pernille Erland Jensen, M. Abouelnaga, Mohamed A. Salem, Marliin Koolmeister, Mengistu Legesse, Tadesse Eguale, Annamari Heikinheimo, Soizick Le Guyader, Julien Schaeffer, José E. Villacís, Bakary Sanneh, Lile Malania, Andreas Nitsche, Annika Brinkmann, Sara Schubert, Sina Hesse, Thomas U. Berendonk, Courage Kosi Setsoafia Saba, Jibril Mohammed, Patrick Kwame Feglo, Regina Ama Banu, Charalampos Kotzamanidis, Efthymios Lytras, Sergio A. Lickes, Béla Kocsis, Norbert Solymosi, Thorunn R. Thorsteinsdottir, A. A. Mohamed Hatha, Mamatha Ballal, Sohan Rodney Bangera, Fereshteh Fani   +99 more
openalex   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The Collaborative African Genomics Network (CAfGEN): Applying Genomic technologies to probe host factors important to the progression of HIV and HIV-tuberculosis infection in sub-Saharan Africa [version 1; peer review: 2 approved]

AAS Open Research, 2018
Background: The Human Heredity and Health in Africa consortium (H3Africa) was conceived to facilitate the application of genomics technologies to improve health across Africa.
Gerald Mboowa, Savannah Mwesigwa, Eric Katagirya, Gaone Retshabile, Busisiwe C. Mlotshwa, Lesedi Williams, Adeodata Kekitiinwa, David Kateete, Eddie Wampande, Misaki Wayengera, Betty Nsangi Kintu, Grace P. Kisitu, Samuel Kyobe, Chester W. Brown, Neil A. Hanchard, Graeme Mardon, Moses Joloba, Gabriel Anabwani, Ed Pettitt, Masego Tsimako-Johnstone, Ishmael Kasvosve, Koketso Maplanka, Sununguko W. Mpoloka, Makhosazana Hlatshwayo, Mogomotsi Matshaba   +24 more
doaj   +1 more source

Comparative genomics of Shiga toxin encoding bacteriophages [PDF]

, 2012
Background Stx bacteriophages are responsible for driving the dissemination of Stx toxin genes (stx) across their bacterial host range. Lysogens carrying Stx phages can cause severe, lifethreatening disease and Stx toxin is an integral virulence factor.
Allison, Heather, Darby, Alistair, Fogg, Paul, McCarthy, Alan, Rooks, David, Smith, Darren, Thomson, Nicholas   +6 more
core   +2 more sources

Genome Projects and the Functional-Genomic Era [PDF]

Combinatorial Chemistry & High Throughput Screening, 2005
The problems we face today in public health as a result of the -- fortunately -- increasing age of people and the requirements of developing countries create an urgent need for new and innovative approaches in medicine and in agronomics. Genomic and functional genomic approaches have a great potential to at least partially solve these problems in the ...
Sauer, S., Konthur, Z., Lehrach, H.
openaire   +3 more sources

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

FEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Anticipation of Personal Genomics Data Enhances Interest and Learning Environment in Genomics and Molecular Biology Undergraduate Courses. [PDF]

PLoS ONE, 2015
An important discussion at colleges is centered on determining more effective models for teaching undergraduates. As personalized genomics has become more common, we hypothesized it could be a valuable tool to make science education more hands on ...
K Scott Weber, Jamie L Jensen, Steven M Johnson   +2 more
doaj   +1 more source