Results 121 to 130 of about 1,731,425 (299)
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Advanced Science, EarlyView.Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang +32 more
wiley +1 more source
A genotype-environment interaction experiment with bacon pigs
, 1963 SUMMARYA genotype-environment interaction experiment was carried out on a total of 140 pigs. Three genotypes, produced by mating an inbred boar of each of the Large White, Landrace and Wessex Saddleback breeds to Large White sows, were fattened on ...
J. W. B. King
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Advanced Science, EarlyView.Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang +21 more
wiley +1 more source
Genetics and Molecular Biology, 2009 Genotype by environment interactions (GEI) have attracted increasing attention in tropical breeding programs because of the variety of production systems involved.
Newton T. Pégolo +4 more
doaj
The Role of Genotype by Environmental Interaction in Plant Breeding
, 2020 A genotype x environment interaction is a change in the relative performance of a character of two or more genotypes measured into two or more environments.
Begna, Temesgen
core
Advanced Science, EarlyView.This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
Yield, Stability, and Adaptability of Hybrid Japonica Rice Varieties in the East Coast of China
AgronomyThe high yield potential and stability of hybrid japonica rice varieties are crucial for sustainable agricultural development and food security. Rice varieties must undergo rigorous testing through multi-site regional trials before being introduced to ...
Rujia Chen +14 more
doaj +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Genotype by Environment Interaction for Grain Yield of Barley Mutant Lines
, 2019 The aim of this study was to examine the genotype by environment interaction for grain yield and to identify high-yielding and stable mutant lines of 6-rowed winter barley under different growing seasons.
Dyulgerov Nikolay, Dyulgerova Boryana
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