Results 201 to 210 of about 130,079 (257)

A Generalizable Multimodal Model for Treatment‐Stratified Risk and Survival Assessment under Real‐World Constraints: A Multi‐Center Study of Colorectal Cancer

Advanced Science, EarlyView.
DAIMS is a multimodal model for treatment stratified risk and survival assessment in colorectal cancer. Training draws on pathology, genomics, and clinical reports, yet inference requires only whole slide images, and adaptation to new cohorts proceeds without target survival outcomes.
Chuangjie Cao, Zheyi Ji, Chang He, Jiying Wang, Xiaoming Luo, Junyi Liu, Xiaohu Jing, Fang Yan, Yirong Chen, Linhao Qu, Sen Yang, Le Lu, Yuming Jiang, Xiyue Wang, Chengyun Dou, Junhan Zhao   +15 more
wiley   +1 more source

Genotype by environment interaction effect and fresh root yield stability of cassava genotypes under contrasting nitrogen regimes. [PDF]

Sci Rep
Mbe JO, Dzidzienyo D, Abah SP, Njoku DN, Aghogho CI, Onyeka J, Tongoona P, Egesi C.   +7 more
europepmc   +1 more source

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

Advanced Science, EarlyView.
LAPTM5 functions as a critical molecular scaffold bridging PGAM5 and VAMP to facilitate PGAM5‐mediated dephosphorylation of VAMP8. This cascade promotes autophagosome‐lysosome fusion, restores impaired autophagic flux, and clears damaged mitochondria, thereby mitigating cellular oxidative stress and systemic inflammation.
Lang Jiang, Qilan Li, Hao Liu, Xuehui Gao, Hongyu Nie, Lang Chen, Mei He, Xuefeng Li, Xiangming Fang, Jiqian Xu, Hao Zhang, Jiahong Xia, You Shang   +12 more
wiley   +1 more source

Investigating genotype by environment interaction for beef cattle fertility traits in commercial herds in northern Australia with multi-trait analysis. [PDF]

Genet Sel Evol
Copley JP, Hayes BJ, Ross EM, Speight S, Fordyce G, Wood BJ, Engle BN.   +6 more
europepmc   +1 more source

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

Advanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong, Wenjun Zhou, Yuxiang Sun, Zihan Huang, Zhiyue Liu, Udhaya Kumar. S, Chenyan Li, Yi Lu, Chengchuang Song, Veronica C. Ciliberto, Makenna Mack, Lana E. Kim, Zhaoyong Hu, Fang Luo, Aihua Cao, Zheng Sun   +15 more
wiley   +1 more source

Genotype x environment interaction and yield stability of soybean (Glycine max l.) genotypes in multi-environment trials (METs) in Nigeria. [PDF]

Heliyon
Abebe AT, Adewumi AS, Adebayo MA, Shaahu A, Mushoriwa H, Alabi T, Derera J, Agbona A, Chigeza G.   +8 more
europepmc   +1 more source

Deciphering genotype-by-environment interaction of grass pea genotypes under rain-fed conditions and emphasizing the role of monthly rainfall. [PDF]

BMC Plant Biol
Maleki HH, Vaezi B, Jozeyan A, Mirzaei A, Darvishzadeh R, Dashti S, Abdi H, Zeinalzadeh-Tabrizi H.   +7 more
europepmc   +1 more source

Deciphering genotype-by-environment interaction in new soybean lines based on multiple traits using different adaptability and stability methods. [PDF]

Food Sci Nutr
Majidian P, Masoudi B, Hezarjaribi E, Razmi N, Peyghamzadeh K, Gholizadeh A.   +5 more
europepmc   +1 more source

AMMI and GGE biplot analysis of genotype by environment interaction for yield and yield contributing traits in confectionery groundnut. [PDF]

Sci Rep
Kona P, Ajay BC, Gangadhara K, Kumar N, Choudhary RR, Mahatma MK, Singh S, Reddy KK, Bera SK, Sangh C, Rani K, Chavada Z, Solanki KD.   +12 more
europepmc   +1 more source

Genotype-by-environment interaction and stability analysis of grain yield of bread wheat (Triticum aestivum L.) genotypes using AMMI and GGE biplot analyses. [PDF]

Heliyon
Mullualem D, Tsega A, Mengie T, Fentie D, Kassa Z, Fassil A, Wondaferew D, Gelaw TA, Astatkie T.   +8 more
europepmc   +1 more source