Results 41 to 50 of about 302,540 (297)

Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits [PDF]

, 2013
While genome-wide association studies (GWAS) and candidate gene approaches have identified many genetic variants that contribute to disease risk as main effects, the impact of genotype by environment (GxE) interactions remains rather under-surveyed.
Arnett, Donna K, Borecki, Ingrid B, Lai, Chao-Qiang, Lee, Yu-Chi, Li, Duo, Ordovas, Jose M, Parnell, Laurence D, Richardson, Kris, Shen, Jian, Smith, Caren E, Zheng, Ju-Sheng   +10 more
core   +4 more sources

Parametric Bootstrap Methods for Testing Multiplicative Terms in GGE and AMMI Models [PDF]

, 2014
The genotype main effects and genotype-by-environment interaction effects (GGE) model and the additive main effects and multiplicative interaction (AMMI) model are two common models for analysis of genotype-by-environment data.
Bradley, Cornelius, Cornelius, Cornelius, Denis, Dias, Dias, Eastment, Efron, Finlay, Gauch, Gauch, Gauch, Gauch, Gollob, Johnson, Liu, Mandel, Mandel, Marasinghe, Muirhead, Ng, Piepho, Piepho, Piepho, Piepho, Schott, Searle, Smith, Tsujitani, Tukey, van Eeuwijk, van Eeuwijk, Wold, Yan, Yan, Yan, Yan, Yang, Yates, Yochmowitz   +40 more
core   +1 more source

Hepatitis C virus NS5A targets the nucleosome assembly protein NAP1L1 to control the innate cellular response [PDF]

, 2017
Hepatitis C virus (HCV) is a single-stranded positive-sense RNA hepatotropic virus. Despite cellular defenses, HCV is able to replicate in hepatocytes and to establish a chronic infection that could lead to severe complications and hepatocellular ...
Cesarec, Mia, Da Silva Filipe, Ana, Licastro, Danilo, Marcello, Alessandro, McLauchlan, John, Çevik, Recep Emrah   +5 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

DRD4-exonIII-VNTR moderates the effect of childhood adversities on emotional resilience in young-adults [PDF]

, 2015
Most individuals successfully maintain psychological well-being even when exposed to trauma or adversity. Emotional resilience or the ability to thrive in the face of adversity is determined by complex interactions between genetic makeup, previous ...
Anstey, Kaarin, Cherbuin, Nicolas, Das, Debjani, Easteal, Simon, Tan, Xiaoyun   +4 more
core   +1 more source

Genetic variability, stability and heritability for quality and yield characteristics in provitamin A cassava varieties [PDF]

, 2020
Open Access Article; Published online: 25 Jan 2020Cassava is widely consumed in many areas of Africa, including Ghana, and is a major part of most household diets.
Biljon, A. van, Kulakow, P., Labuschagne, M., Manu-Aduening, J., Parkes, E., Peprah, B.B.   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Grain yield stability analysis using parametric and nonparametric statistics in oat (Avena sativa L.) genotypes in Ethiopia

Grassland Research, 2023
Background The performance of oat genotypes differs across environments due to variations in biotic and abiotic factors. Thus, evaluation of oat genotypes across diverse environments is very important to identify superior and stable genotypes for yield ...
Gezahagn Kebede, Walelign Worku, Habte Jifar, Fekede Feyissa   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Adaptation of One-Flowered Vetch (Vicia articulata Hornem.) to Mediterranean Rain Fed Conditions

Agronomy, 2020
One-flower vetch (Vicia articulata) was widely cultivated in the Mediterranean Basin in the past but is currently underutilized. Valuable germplasm collections are stored in genebanks, which are poorly characterized.
Diego Rubiales, Fernando Flores
doaj   +1 more source