Results 51 to 60 of about 1,731,425 (299)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Genetic variance and genotype reaction norms in response to larval food manipulation for a trait important in scorpionfly sperm competition.

, 2008
Engqvist L. Genetic variance and genotype reaction norms in response to larval food manipulation for a trait important in scorpionfly sperm competition. Functional Ecology. 2008;22(1):070915213639001-???Sperm competition is an important attribute of many
L. Engqvist, Engqvist, Leif ; https://orcid.org/   +1 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Evaluating Genotype × Environment Interactions of Yield Traits and Adaptability in Rice Cultivars Grown under Temperate, Subtropical and Tropical Environments

Agriculture, 2021
Rice yield is a complex trait that is strongly affected by environment and genotype × environment interaction (GEI) effects. Consideration of GEI in diverse environments facilitates the accurate identification of optimal genotypes with high yield ...
Xing Huang, Su Jang, Backki Kim, Zhongze Piao, Edilberto Redona, Hee-Jong Koh   +5 more
doaj   +1 more source

Genotype-by-environment (temperature-humidity) interaction of milk production traits in Australian Holstein cattle

, 2020
© 2020 American Dairy Science Association Dairying in Australia is practiced in highly diverse climatic conditions and production systems, which means that re-ranking of genotypes could occur across environments that vary in temperature and humidity—that
Evans Kiptoo Cheruiyot (9482492), Mary Abdelsayed (9474362), Jennie Pryce (9477563), Mekonnen Haile-Mariam (14228126), Benjamin Cocks (9477566), TTT Nguyen (9757946)   +5 more
core   +1 more source

Proportion of the variations in heartwood color traits explained by genotype, environment, and the interaction between genotype and environment (i.e., plasticity).

, 2022
Proportion of the variations in heartwood color traits explained by genotype, environment, and the interaction between genotype and environment (i.e., plasticity).
Yoshihiko Tsumura (408539), Takahiro Yoshida (461333), Ryota Endo (2713057), Tokuko Ujino-Ihara (487192), Asako Matsumoto (5440334), Kana Yamashita (8368014), Yoshimi Sakai (836800), Ryouichi Kusano (13007532), Hideki Mori (1709440), Seiichi Kanetani (4694275), Takeshi Fujiwara (170826), Kentaro Uchiyama (487189), Yoshinari Moriguchi (487191), Saneyoshi Ueno (408537)   +13 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The theory on and software simulating large-scale genomic data for genotype-by-environment interactions

BMC Genomics, 2021
Background With the emphasis on analysing genotype-by-environment interactions within the framework of genomic selection and genome-wide association analysis, there is an increasing demand for reliable tools that can be used to simulate large-scale ...
Xiujin Li, Hailiang Song, Zhe Zhang, Yunmao Huang, Qin Zhang, Xiangdong Ding   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source