Results 71 to 80 of about 1,731,425 (299)
Despite QTL mapping being a routine procedure in plant breeding, approaches that fully exploit data from multi-trait multi-environment (MTME) trials are limited.
Crossa, J. +4 more
core +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Environmental stratification based on a 28 x 28 diallel of open-pollinated maize varieties
The objective of this study was to assess the representativeness of the test environments used by the maize breeding program of Embrapa in the first phase of genotype evaluation.
Cleso Antônio Patto Pacheco +9 more
doaj
The low productivity of tef needs to be improved through concerted research efforts. Multi-environment variety trial was conducted on 14 tef genotypes at Adet, Mota, and Bichena from 2016 to 2018 to identify and recommend high yielding and stable ...
Sewagegne Tariku +5 more
doaj
Genotype-environment interaction in some rice mutants (Oryza sativa L.) [PDF]
Stability performance and genotype-environment (G×E) interactions were investigated for yield and yield components of seven rice genotypes at eight cultural soil environments and were measured through linear regression and deviation from regression.
Uddin, M. I. +5 more
core
Genes exhibiting significant (FDR-adjusted P-value |2|) activity genotype-by-environment interaction.
Bruce R. Southey (19329) +6 more
core +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
A resampling test for principal component analysis of genotype-by-environment interaction [PDF]
In crop science, genotype-by-environment interaction is oftenexplored using the "genotype main effects and genotype-by-environmentinteraction effects" (GGE) model.
Forkman, Johannes
core +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source

