Results 71 to 80 of about 302,540 (297)

Predicting spring barley yield from variety-specific yield potential, disease resistance and straw length, and from environment-specific disease loads and weed pressure [PDF]

, 2008
For low-input crop production, well-characterised varieties increase the possibilities of managing diseases and weeds. This analysis aims at developing a framework for analyzing grain yield using external varietal information about disease resistance ...
Hansen, P.K., Hovmøller, M.S., Kristensen, K., Pinnschmidt, H.O., Østergård, H.   +4 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Genome-wide association and genotype by environment interactions for growth traits in U.S. Red Angus cattle

BMC Genomics, 2022
Background Genotypic information produced from single nucleotide polymorphism (SNP) arrays has routinely been used to identify genomic regions associated with complex traits in beef and dairy cattle.
Johanna L. Smith, Miranda L. Wilson, Sara M. Nilson, Troy N. Rowan, Robert D. Schnabel, Jared E. Decker, Christopher M. Seabury   +6 more
doaj   +1 more source

Association studies including genotype by environment interactions: prospects and limits [PDF]

BMC Genetics, 2014
Association mapping studies offer great promise to identify polymorphisms associated with phenotypes and for understanding the genetic basis of quantitative trait variation. To date, almost all association mapping studies based on structured plant populations examined the main effects of genetic factors on the trait but did not deal with interactions ...
Saidou, Abdoul Aziz, Thuillet, Anne Celine, Couderc, Marie, Mariac, Cédric, Vigouroux, Yves   +4 more
openaire   +7 more sources

Interaksi Genotipe X Lingkungan Untuk Hasil Gabah Padi Sawah [PDF]

, 2016
Grain yield of rice is determined by genotype (G), environment (E), and interaction between genotype x environment (G x E). Variety can achieve its maximum yield potential if it is grown in suitable environments.
Abdullah, B. (Buang), Aswidinnoor, H. (H), Daradjat, A. A. (Aan), Gunarsih, C. (Cucu), Hanarida, I. (Ida), Muliarta, I. G. (I), Nafisah, N. (Nafisah), Nugraha, Y. (Yudhistira), Sitaresmi, T. (Trias), Suprihatno, B. (B)   +9 more
core  

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Phenotypic robustness can increase phenotypic variability after non-genetic perturbations in gene regulatory circuits [PDF]

, 2010
Non-genetic perturbations, such as environmental change or developmental noise, can induce novel phenotypes. If an induced phenotype confers a fitness advantage, selection may promote its genetic stabilization. Non-genetic perturbations can thus initiate
Ancel, Aubret, Azevedo, Bergman, Ciliberti, Ciliberti, Cooper, Davidson, de Jong, de Visser, Draghi, Draghi, Eldar, Elowitz, Espinosa-Soto, Espinosa-Soto, Ferrada, Fraser, Gibson, Gilbert, Gomez-Mestre, Griswold, Hall, Hermisson, Kim, Kimbrell, Kondrashov, Lande, Ledon-Rettig, Lehner, Levy, Lipman, Martin, Martin, Masel, Masel, Masel, McAdams, Meiklejohn, Moczek, Newman, Orr, Palmer, Palmer, Pigliucci, Pigliucci, Price, Proulx, Prud'homme, Raj, Rice, Roberts, Rodrigues, Rutherford, Schmalhausen, Schultes, Schuster, Shubin, Siegal, Snell-Rood, Sollars, Suzuki, Tirosh, van Nimwegen, Waddington, Waddington, Wagner, Wagner, Wagner, Wagner, Wagner, West-Eberhard, West-Eberhard, Wray   +73 more
core   +3 more sources

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

The impact of imprecisely measured covariates on estimating gene-environment interactions [PDF]

, 2006
BACKGROUND The effects of measurement error in epidemiological exposures and confounders on estimated effects of exposure are well described, but the effects on estimates for gene-environment interactions has received rather less attention.
Cade, J.E., Gilthorpe, M.S., Greenwood, D.C.   +2 more
core   +2 more sources

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source