Results 81 to 90 of about 302,540 (297)

Genome-wide association and genotype by environment interactions for growth traits in U.S. Gelbvieh cattle

open access: yesBMC Genomics, 2019
Background Single nucleotide polymorphism (SNP) arrays have facilitated discovery of genetic markers associated with complex traits in domestic cattle; thereby enabling modern breeding and selection programs.
Johanna L. Smith   +7 more
doaj   +1 more source

Analysis of trait stability of soybean cultivated under various environmental conditions [PDF]

open access: yesJournal of Water and Land Development
Soybean ( Glycine max (L.) Merrill.) yielding potential depends on environmental conditions (precipitation, temperature, soil). The aim of the work was to evaluate stability of yielding (and other traits) of three soybean cultivars (Abelina, SG Anser ...
Katarzyna Rymuza, Elżbieta Radzka
doaj   +1 more source

Genotype by environment interaction for gene expression in Drosophila melanogaster

open access: yesNature Communications, 2020
Huang et al. show that developing under different temperatures changes the genetic architecture of regulatory variation in Drosophila melanogaster gene expression yet the co-expression network remains robust.
Wen Huang   +4 more
doaj   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

open access: yesAdvanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram   +10 more
wiley   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

open access: yesAdvanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang   +13 more
wiley   +1 more source

Bayesian semiparametric analysis for two-phase studies of gene-environment interaction [PDF]

open access: yes, 2013
The two-phase sampling design is a cost-efficient way of collecting expensive covariate information on a judiciously selected subsample. It is natural to apply such a strategy for collecting genetic data in a subsample enriched for exposure to ...
Ahn, Jaeil   +3 more
core   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

Genotype x environment interaction in cowpea by mixed models

open access: yesRevista Ciência Agronômica
Several methods have been proposed to measure effects of genotype × environment interaction (G×E) on various traits of interest of plant species, such as grain yield.
Leonardo Castelo Branco Carvalho   +3 more
doaj   +1 more source

Study of a Novel Bi‐Layered Thermoplastic Polyurethane Patch for Congenital Diaphragmatic Hernia

open access: yesAdvanced Materials Interfaces, EarlyView.
Large congenital diaphragmatic hernia remains a challenge due to the poor compatibility of current prostheses. To tackle this problem, a bilayer thermoplastic polyurethane patch with tunable mechanical properties is engineered, whose fibrous side supports rapid fibroblast and myoblast colonization, while the smooth film limits adhesions.
Guillaume Leks   +14 more
wiley   +1 more source

Genotype by environment interaction and breeding for robustness in livestock

open access: yesFrontiers in Genetics, 2015
The increasing size of the human population is projected to result in an increase in meat consumption. However, at the same time, the dominant position of meat as the centre of meals is on the decline. Modern objections to the consumption of meat include
Wendy Mercedes Rauw, Luis eGomez Raya
doaj   +1 more source

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