Results 111 to 120 of about 2,304,211 (377)

Examination of the Monoamine Oxidase A Gene Promoter on Motivation to Exercise and Levels of Voluntary Physical Activity [PDF]

open access: yes, 2017
Purpose: The purpose of this study was to examine the genetic basis underlying voluntary exercise. Monoamine oxidase A (MAO-A) is an enzyme that acts on monoamine neurotransmitters, such as dopamine, to cause inactivation. There are several polymorphisms
Kinney, Erin M.
core   +4 more sources

Genetic Risk of MASLD in Mongolians: Role of PNPLA3 and FTO SNPs

open access: yesCurrent Issues in Molecular Biology
Background: This study aimed to determine the association between PNPLA3 rs738409, rs2896019, and FTO rs9939609, rs17817449 single-nucleotide polymorphisms and the risk of metabolic dysfunction-associated steatotic liver disease (MASLD) in Mongolian ...
Yumchinsuren Tsedendorj   +11 more
doaj   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

MOLECULAR CHARACTERIZATION OF ROTAVIRUSES ISOLATED FROM CALVES WITH BOVINE NEONATAL DIARRHEA (BND) IN COLOMBIA

open access: yesInfectio, 2018
Bovine rotaviruses are one of the main agents involved in the presentation of Bovine Neonatal Diarrhea (BND), a disease that affects calves in the first month of life.
Dolly Pardo-Mora
doaj   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer   +11 more
wiley   +1 more source

Phenotypical and genotypical resistance testing of Pasteurella multocida isolated from different animal species in Austria

open access: yesFrontiers in Veterinary Science
IntroductionPasteurella multocida is an economically important pathogen in veterinary medicine. Data on its antimicrobial resistance vary widely across regions. Furthermore, most of the found literature focuses on phenotypic resistance testing.
Leonard Barta   +6 more
doaj   +1 more source

Translating a Preclinically Tested 15 Hz rTMS Protocol to Humans With Chronic Spinal Cord Injury: A Safety and Feasibility Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Repetitive transcranial magnetic stimulation (rTMS) is a non‐invasive brain stimulation strategy with a demonstrated potential to reinforce the residual pathways after a spinal cord injury (SCI). A preclinically tested high‐frequency (15 Hz) rTMS (15 Hz rTMS) protocol was shown to induce corticospinal tract axon regeneration growth ...
Nabila Brihmat   +8 more
wiley   +1 more source

Combined genetic and genomic approaches to characterize a durable Hevea resistance to South American leaf blight : S01T07 [PDF]

open access: yes, 2013
The South American Leaf Blight (SALB), due to the Ascomycota Microcyclus ulei, threatens the world production of natural rubber, based on the cultivation of nearly only one species: the tropical tree Hevea brasiliensis.
Berger, Angélique   +9 more
core  

The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh   +22 more
wiley   +1 more source

Gene Regulatory Changes Associated With Phenological Transitions in an Ecologically Significant Tree Species

open access: yesPlant-Environment Interactions
Climate change is driving earlier spring leaf‐out across temperate regions, but the genetic mechanisms and environmental interactions underlying this variability are poorly understood.
Theresa Caso‐McHugh   +3 more
doaj   +1 more source

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