Results 121 to 130 of about 2,122,472 (401)
Genotype networks in metabolic reaction spaces [PDF]
BMC Systems Biology, 4:30 (2010)
http://www.biomedcentral.com/1752-0509/4/30/, 2010 Background: A metabolic genotype comprises all chemical reactions an organism can catalyze via enzymes encoded in its genome. A genotype is viable in a given environment if it is capable of producing all biomass components the organism needs to survive and reproduce.
arxiv
Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis
JAMA Neurology, 2017 Importance It is unclear whether female carriers of the apolipoprotein E (APOE) &egr;4 allele are at greater risk of developing Alzheimer disease (AD) than men, and the sex-dependent association of mild cognitive impairment (MCI) and APOE has not been ...
S. Neu +23 more
semanticscholar +1 more source
Biomedical Papers, 2015 Aims: A germline SNP (rs61764370) is located in a let-7 complementary site (LCS6) in the 3'UTR of KRAS oncogene, and it was found to alter the binding capability of the mature let-7 microRNA to the KRAS mRNA.
Magdalena Uvirova +6 more
doaj +1 more source
Inferring genotyping error rates from genotyped trios [PDF]
arXiv, 2011 Genotyping errors are known to influence the power of both family-based and case-control studies in the genetics of complex disease. Estimating genotyping error rate in a given dataset can be complex, but when family information is available error rates can be inferred from the patterns of Mendelian inheritance between parents and offspring.
arxiv
Grain Characteristics, Chemical Composition, and Functional Properties of Rye (Secale cereale L.) As Influenced by Genotype and Harvest Year [PDF]
, 2004 Grain characteristic, chemical composition, and functional properties of rye were measured in 19 different cultivars grown in one location in up to 3 years.
Andersen, S.B. +4 more
core +1 more source
Host genotype and age shape the leaf and root microbiomes of a wild perennial plant
Nature Communications, 2016 Bacteria living on and in leaves and roots influence many aspects of plant health, so the extent of a plant’s genetic control over its microbiota is of great interest to crop breeders and evolutionary biologists.
Maggie R. Wagner +5 more
semanticscholar +1 more source
Molecular genotype in migraine [PDF]
The Journal of Headache and Pain, 2015 Migraine is an episodic brain disorder with disabling attacks of headache that are associated with nausea, vomiting, and hypersensitivity to light, sound, and smell. According to major criteria of the International Classification of Headache Disorders (ICHD-II) from the International Headache Society (IHS), migraine is divided into two main subtypes ...
Gaetano S. Grieco +3 more
openaire +3 more sources
Tell Me What You Eat and I Will Tell You Your Sociotype: Coping with Diabesity
Rambam Maimonides Medical Journal, 2012 The term sociotype has been introduced to describe the dynamic relationship of an individual with his/her social environment throughout life. The sociotype is a conceptual framework to highlight, in addition to bio-medical pathways, the psycho-social and
Sabina De Geest
doaj +1 more source
Including copy number variation in association studies to predict genotypic values [PDF]
, 2010 The objective of this study was to investigate, both empirically and deterministically, the ability to explain genetic variation resulting from a copy number polymorphism (CNP) by including the CNP, either by its genotype or by a continuous derivation ...
Calus, M.P.L. +2 more
core +2 more sources
Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection.
New England Journal of Medicine, 2015 BACKGROUND In phase 2 trials, treatment with the combination of the nucleotide polymerase inhibitor sofosbuvir and the NS5A inhibitor velpatasvir resulted in high rates of sustained virologic response in patients chronically infected with hepatitis C ...
G. Foster +34 more
semanticscholar +1 more source