Results 121 to 130 of about 2,216,855 (328)
Genotype, Phenotype and Mating Behavior of Drosophila melanogaster [PDF]
, 1962 B. W. Geer, M. M. Green
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Next-generation genotype imputation service and methods
Nature Genetics, 2016 Sayantani Das +20 more
semanticscholar +1 more source
From Lab to Market: Paper‐Based CRISPR Diagnostics and Commercialization Pathways
Advanced Sensor Research, EarlyView.Paper‐based CRISPR diagnostics represents one of the most widely commercialized CRISPR assay technologies, yet challenges remain for broader point‐of‐care use. Abstract The global health landscape is continually challenged by infectious diseases that can swiftly escalate into pandemics, underscoring the need for rapid, accurate, and cost‐effective ...
Selen Dalgan, Qingshan Wei
wiley +1 more source
Effects of neutral selection on the evolution of molecular species
, 1997 We introduce a new model of evolution on a fitness landscape possessing a tunable degree of neutrality. The model allows us to study the general properties of molecular species undergoing neutral evolution.
Engelhardt, Robin, Newman, M. E. J.
core +1 more source
Loss of NR2F6 Protects from Salmonella Typhimurium Infection
Advanced Science, EarlyView.Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk +8 more
wiley +1 more source
Advanced Science, EarlyView.ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu +15 more
wiley +1 more source
Selection against the variegated genotype in Barbarea vulgaris [PDF]
, 1963 R. A. E. Tilney-Bassett
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A comparison of bayesian methods for haplotype reconstruction from population genotype data.
American Journal of Human Genetics, 2003 M. Stephens, P. Donnelly
semanticscholar +1 more source
LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing
Advanced Science, EarlyView.This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang +15 more
wiley +1 more source
Influence of Sex on Selection II. Contributions of Autosomal Genotypes Having Different Values in the Two Sexes [PDF]
, 1966 B Griffing
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