Results 31 to 40 of about 2,304,211 (377)

Acanthamoeba genotype T4 from the UK and Iran and isolation of the T2 genotype from clinical isolates [PDF]

, 2005
The majority of the keratitis-causing Acanthamoeba isolates are genotype T4. In an attempt to determine whether predominance of T4 isolates in Acanthamoeba keratitis is due to greater virulence or greater prevalence of this genotype, Acanthamoeba ...
Alsam, Amir Hossein Maghsood, Araki-Sasaki, Booton, David Warhurst, De Jonckheere, Debbie Nolder, Gast, James Sissons, Khan, Khan, Khan, Khan, Khan, Kong, Ledee, Marciano-Cabral, Mostafa Rezaian, Naveed Ahmed Khan, Schuster, Stothard, Walochnik   +21 more
core   +1 more source

Priors for Genotyping Polyploids [PDF]

Bioinformatics, 2019
AbstractMotivationEmpirical Bayes techniques to genotype polyploid organisms usually either (i) assume technical artifacts are knowna priorior (ii) estimate technical artifacts simultaneously with the prior genotype distribution. Case (i) is unappealing as it places the onus on the researcher to estimate these artifacts, or to ensure that there are no ...
Gerard, David, Ferrão, Luís Felipe Ventorim   +1 more
openaire   +4 more sources

A comparison of genotyping arrays [PDF]

European Journal of Human Genetics, 2021
AbstractArray technology to genotype single-nucleotide variants (SNVs) is widely used in genome-wide association studies (GWAS), clinical diagnostics, and linkage studies. Arrays have undergone a tremendous growth in both number and content over recent years making a comprehensive comparison all the more important. We have compared 28 genotyping arrays
Joost A. M. Verlouw, Eva Clemens, Jard H. de Vries, Oliver Zolk, Annemieke J. M. H. Verkerk, Antoinette am Zehnhoff-Dinnesen, Carolina Medina-Gomez, Claudia Lanvers-Kaminsky, Fernando Rivadeneira, Thorsten Langer, Joyce B. J. van Meurs, Marry M. van den Heuvel-Eibrink, André G. Uitterlinden, Linda Broer   +13 more
openaire   +4 more sources

A Sub-Type of Familial Pancreatic Cancer: Evidence and Implications of Loss-of-Function Polymorphisms in Indoleamine-2,3-Dioxygenase-2. [PDF]

, 2018
BACKGROUND: Variation in an individual\u27s genetic status can impact the development of pancreatic ductal adenocarcinoma; however, the majority of familial pancreatic cancers (FPC) cannot yet be attributed to a specific inherited mutation.
Brody, Jonathan, Cozzitorto, Joseph A., Goetz, Austin, Lavu, Harish, Muller, Alexander J., Nevler, Avinoam, Prendergast, George C., Winter, Jordan M., Yeo, Charles, Yeo, Theresa P.   +9 more
core   +2 more sources

Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy on Ischemic Outcomes After Percutaneous Coronary Intervention: The TAILOR-PCI Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance After percutaneous coronary intervention (PCI), patients with CYP2C19*2 or *3 loss-of-function (LOF) variants treated with clopidogrel have increased risk of ischemic events.
N. Pereira, M. Farkouh, D. So, R. Lennon, N. Geller, V. Mathew, M. Bell, J. Bae, M. Jeong, Ivan J. Chavez, Paul Gordon, J. Abbott, C. Cagin, L. Baudhuin, Yi-Ping Fu, S. Goodman, S. Goodman, Ahmed A Hasan, E. Iturriaga, A. Lerman, M. Sidhu, J. Tanguay, Liewei Wang, R. Weinshilboum, R. Welsh, Y. Rosenberg, K. Bailey, C. Rihal   +27 more
semanticscholar   +1 more source

Genotyping—From Genomic DNA to Genotype in a Single Tube [PDF]

Angewandte Chemie International Edition, 2005
AbstractNucleotide variations in the human genome, such as single‐nucleotide polymorphisms, have been researched more intensively since it became apparent that these deviations are linked to various diseases and also several side effects of drugs. The investigation of genomic DNA in the laboratory requires routine methods that are time‐, labour‐, and ...
Strerath, Michael, Marx, Andreas
openaire   +4 more sources

Assessment of Seed Viability Before and After Storage in Forage Pea (Pisum sativum L. var. arvense) Using Field and Laboratory Methods

Plants
This study aimed to evaluate the effects of different storage conditions on seed viability, vigor, and agronomic performance in six forage pea (Pisum sativum L. var. arvense) cultivars: Uysal, Özkaynak, Kurtbey, Ürünlü, Taşkent, and Nany.
Serhat Akyüz, Emine Serap Kizil Aydemir, Serkan Ateş   +2 more
doaj   +1 more source

ENVIRONMENTAL STUDY OF NEW EARLY-MATURING BARLEY LINES

Труды по прикладной ботанике, генетике и селекции, 2018
Early-maturing lines L-1610 and L-1611 developed and selected as high-yielding at the Leningrad Research Institute of Agriculture "Belogorka" were studied at Kotlas Breeding Experimental Station (Arkhangelsk region). As the result of the study in Kotlas,
O. B. Batakova, V. A. Korelina, N. V. Ivanova, A. V. Anisimova, O. N. Kovaleva   +4 more
doaj   +1 more source

Phenotypes and genotypes of macrolide-resistant Streptococcus pneumoniae in Serbia [PDF]

Archives of Biological Sciences, 2014
Although macrolides are widely used for treating pneumococcal infections, an increase in macrolide resistance might compromise their use. The objective of this study was to determine the prevalence of macrolide-resistant phenotypes and genotypes
Hadnađev Mirjana, Gajić Ina, Mijac Vera, Kurucin Tatjana, Považan Anika, Vulin Aleksandra, Opavski Nataša   +6 more
doaj   +1 more source

souporcell: Robust clustering of single cell RNAseq by genotype without reference genotypes

Nature Methods, 2020
Methods to deconvolve single-cell RNA-sequencing (scRNA-seq) data are necessary for samples containing a mixture of genotypes, whether they are natural or experimentally combined. Multiplexing across donors is a popular experimental design that can avoid
Haynes Heaton, A. Talman, Andrew J. Knights, M. Imaz, Daniel J. Gaffney, R. Durbin, M. Hemberg, M. Lawniczak   +7 more
semanticscholar   +1 more source