Results 231 to 240 of about 26,046,977 (327)

Alpha-1-antitrypsin genotype and allergy

open access: yesWorld Allergy Organization Journal, 2007
A. G. Palma-Carlos, M.L. Palma-Carlos
openaire   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

open access: yesAdvanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li   +15 more
wiley   +1 more source

JSH Guidelines for the Management of Hepatitis C Virus Infection: A 2016 update for genotype 1 and 2

open access: yesHepatology Research, 2016
Y. Asahina   +13 more
semanticscholar   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

open access: yesAdvanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao   +11 more
wiley   +1 more source

Effectiveness of Ledipasvir-Sofosbuvir 12 Weeks After Hepatitis C Virus Genotype 1 Infection and the Factors Associated With Sustained Virologic Response: A Retrospective Study. [PDF]

open access: yesCureus
Alshoaibi IA   +11 more
europepmc   +1 more source

Safety and efficacy of ledipasvir/sofosbuvir for the treatment of genotype 1 hepatitis C in subjects aged 65 years or older

open access: yesHepatology, 2016
S. Saab   +11 more
semanticscholar   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

open access: yesAdvanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She   +14 more
wiley   +1 more source

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