Results 41 to 50 of about 26,046,977 (327)

The effects of an intronic polymorphism in TOMM40 and APOE genotypes in sporadic inclusion body myositis. [PDF]

, 2015
A previous study showed that, in carriers of the apolipoprotein E (APOE) genotype ε3/ε3 or ε3/ε4, the presence of a very long (VL) polyT repeat allele in "translocase of outer mitochondrial membrane 40" (TOMM40) was less frequent in patients with ...
Barohn, R.J., Bettencourt, C., Brady, S., De Bleecker, J., De Paepe, B., Dimachkie, M.M., Fox, Z., Gang, Q., Hanna, M.G., Healy, E., Hilton-Jones, D., Holton, J.L., Houlden, H., Machado, P.M., Mantegazza, R., Mastaglia, F., Moggio, M., Mora, M., Needham, M., Parton, M., Ripolone, M., Shaibani, A., Shieh, P.B., Violano, R., Zanoteli, E., Zanotti, S.   +25 more
core   +1 more source

Suppressor of cytokine signaling 1 expression in peripheral blood mononuclear cells of hepatitis C genotype 1 patients

Journal of the Formosan Medical Association, 2016
While new direct-acting antiviral therapies for hepatitis C virus (HCV) are the standard of care, interferon-α (IFN-α) remains a standard therapy in Taiwan based on its low cost and high response rate to IFN-α-based therapy.
Chuan-Mo Lee, Tsung-Hui Hu, Sheng-Nan Lu, Jing-Houng Wang, Chao-Hung Hung, Chien-Hung Chen, Yi-Hao Yen   +6 more
doaj   +1 more source

Neutralizing antibodies in patients with chronic hepatitis C, genotype 1, against a panel of genotype 1 culture viruses: lack of correlation to treatment outcome. [PDF]

PLoS ONE, 2013
The correlation of neutralizing antibodies to treatment outcome in patients with chronic hepatitis C virus (HCV) infection has not been established.
Jannie Pedersen, Tanja B Jensen, Thomas H R Carlsen, Kristian Schønning, Peer Brehm Christensen, Alex Lund Laursen, Henrik Krarup, Jens Bukh, Nina Weis   +8 more
doaj   +1 more source

Interferon and ribavirin therapy for chronic hepatitis C virus genotype 6: A comparison with genotype 1 [PDF]

, 2003
Because there is a lack of data on the treatment outcome of patients who carry hepatitis C virus (HCV) genotype 6, we conducted a prospective study, to compare the effect of interferon and ribavirin therapy in HCV genotypes 1 and 6, of patients with ...
Chan, AOO, Hui, CK, Lai, CL, Sablon, E, Wong, BCY, Yuen, MF   +5 more
core   +1 more source

Sofosbuvir–velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 hepatitis C who failed direct-acting antivirals

Hepatology International, 2018
Background/purposeIn Japan, there is a growing population of patients with chronic hepatitis C virus (HCV) infection who failed a direct-acting antiviral (DAA)-based regimen.
N. Izumi, T. Takehara, K. Chayama, H. Yatsuhashi, K. Takaguchi, T. Ide, M. Kurosaki, Y. Ueno, H. Toyoda, S. Kakizaki, Yasuhito Tanaka, Y. Kawakami, H. Enomoto, F. Ikeda, D. Jiang, S. De‐oertel, B. McNabb, G. Camus, L. Stamm, D. Brainard, J. Mchutchison, S. Mochida, M. Mizokami   +22 more
semanticscholar   +1 more source

First Steps Towards a Runtime Comparison of Natural and Artificial Evolution

, 2015
Evolutionary algorithms (EAs) form a popular optimisation paradigm inspired by natural evolution. In recent years the field of evolutionary computation has developed a rigorous analytical theory to analyse their runtime on many illustrative problems ...
Heredia, Jorge Pérez, Paixão, Tiago, Sudholt, Dirk, Trubenová, Barbora   +3 more
core   +1 more source

Computing Individual Risks based on Family History in Genetic Disease in the Presence of Competing Risks [PDF]

, 2017
When considering a genetic disease with variable age at onset (ex: diabetes , familial amyloid neuropathy, cancers, etc.), computing the individual risk of the disease based on family history (FH) is of critical interest both for clinicians and patients.
Bouaziz, O, Lefebvre, Antoine, Nuel, G
core   +3 more sources

Genetic evolution of classical swine fever virus under immune environments conditioned by genotype 1‐based modified live virus vaccine

Transboundary and Emerging Diseases, 2018
Modified live vaccines (MLVs) based on genotype 1 strains, particularly C-strain, have been used to prevent and control classical swine fever virus (CSFV) worldwide.
S. Yoo, T. Kwon, K. Kang, H. Kim, S. Kang, J. Richt, Y. Lyoo   +6 more
semanticscholar   +1 more source

Treatment approach in chronic hepatitis C infection

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2016
Purpose: We aimed to evaluate retrospectively the results of treatment of patients with chronic hepatitis C in our clinic. Material and Methods: We evaluated the treatment results of 109 patients who treated with the diagnosis of chronic hepatitis C ...
Suheyla Komur, Ferit Kuscu, Aslihan Ulu, Ayse Seza inal, Behice Kurtaran, Yesim Tasova, Hasan S. Z. Aksu   +6 more
doaj   +1 more source

Influence of Crohn’s disease related polymorphisms in innate immune function on ileal microbiome [PDF]

, 2019
We have previously identified NOD2 genotype and inflammatory bowel diseases (IBD) phenotype, as associated with shifts in the ileal microbiome (“dysbiosis”) in a patient cohort.
Ciorba, Matthew A, Davidson, Nicholas O, Frank, Daniel N, Gathungu, Grace, Li, Ellen, Nelson, Leah M, Robertson, Charles E, Sartor, R. Balfour, Shiekh, Shehzad S, Tian, Xinyu, Wang, Xuefeng, Wolber, Ashley, Zhang, Yuanhao, Zhu, Wei   +13 more
core   +3 more sources