Results 261 to 270 of about 706,514 (296)

Hepatitis C Virus Genotypes 1a and 1b Mixed Infections

Vox Sanguinis, 1997
AbstractIn response to Poljak and Seme's letter, we would like to point out that the manuscript published in another journal [1], although based on the same study population, was only meant to discuss the results of Pawlotsky et al. [2], who claimed that hepatitis C virus (HCV) genotype 3a was the predominant type among injecting drug users (IDUs) in ...
V. Soriano, R. Bravo, J. García‐Samaniego   +2 more
openaire   +1 more source

Development of cell culture infectious clones for hepatitis C virus genotype 1b and transcription analysis of 1b-infected hepatoma cells

Antiviral Research, 2021
Globally, hepatitis C virus (HCV) genotype 1b is the most prevalent, and its infection has been found to associate with a higher risk of hepatocellular carcinoma (HCC) than other genotype viruses. However, an efficient infectious HCV genotype 1b culture system is unavailable, which has largely hampered the study of this important genotype virus.
Jinqian Li, Qing Zhou, Liang Rong, Dade Rong, Yang Yang, Jiawei Hao, Zhenzhen Zhang, Ling Ma, Guirong Rao, Yuanping Zhou, Fei Xiao, Chengyao Li, Haihe Wang, Yi-Ping Li   +13 more
openaire   +2 more sources

Emergence of Hepatitis C Virus Genotype Recombinant Forms 2k/1b in Georgia

Clinical Laboratory, 2016
Hepatitis C virus (HCV) evolution is thought to proceed by mutations within the six major genotypes. Studies of HCV recombinant genotypes in different parts of the world have recently been initiated. Only a few cases of recombination have been identified worldwide, predominantly in Eastern Europe and Asia.
Mamuka, Zakalashvili, Michael, Weizenegger, Jan, Bartel, Monika, Markowski, Jaba, Zarqua, Salome, Kavsadze, Ketevan, Kvatadze, George, Basheleishvili, Tamar, Phirtskhalaishvili, Tamar, Dzagania, Lela, Zangurashvili, Nino, Kankia, Nino, Jashiashvili, Maka, Lomidze, Tengiz, Telia, Vakhtang, Kerashvili, Maia, Zhamutashvili, Nikoloz, Abramishvili, Irakli, Rtskhiladze, David, Metreveli   +19 more
openaire   +2 more sources

Detergent-induced activation of the hepatitis C virus genotype 1b RNA polymerase

Gene, 2012
Recently, we found that sphingomyelin bound and activated hepatitis C virus (HCV) 1b RNA polymerase (RdRp), thereby recruiting the HCV replication complex into lipid raft structures. Detergents are commonly used for resolving lipids and purifying proteins, including HCV RdRp.
Leiyun, Weng, Michinori, Kohara, Takaji, Wakita, Kunitada, Shimotohno, Tetsuya, Toyoda   +4 more
openaire   +2 more sources

Serotonin receptor 1B (HTR1B) genotype associated with milk production traits in cattle

Research in Veterinary Science, 2008
Serotonin receptor 1B (HTR1B) is one of the 14 different identified serotonin receptors which are involved in the regulation of behaviors such as sleep, fear, aggression, mood, and feeding. The aims of this study were to characterize polymorphisms in the 5' coding and the 3' flanking regions of the bovine HTR1B gene among Chinese Holsteins and to ...
C L, Zhang, H, Chen, Y H, Wang, R F, Zhang, X Y, Lan, C Z, Lei, L, Zhang, A L, Zhang, S R, Hu   +8 more
openaire   +2 more sources

Transient replication of a hepatitis C virus genotype 1b replicon chimera encoding NS5A-5B from genotype 3a

Journal of Virological Methods, 2014
Although hepatitis C virus (HCV) is a pathogen of global significance, experimental therapies in current clinical development include highly efficacious all-oral combinations of HCV direct-acting antivirals (DAAs). If approved for use, these new treatment regimens will impact dramatically upon our capacity to eradicate HCV in the majority of virus ...
Helen, Kylefjord, Axel, Danielsson, Susanne, Sedig, Oscar, Belda, Daniel, Wiktelius, Lotta, Vrang, Paul, Targett-Adams   +6 more
openaire   +2 more sources

Amantadine monotherapy of chronic hepatitis C patients infected with genotype 1b.

1998
[No abstract available]
Senturk, H, Mert, A, Akdogan, M, Tabak, F, Basaran, G, Turkoglu, S, Ozbay, G   +6 more
openaire   +2 more sources

HCV NS5A mutations in europeans infected by genotype 1b

Gastroenterology, 1998
S, Magrin, C, Fabiano, F, Gianguzza, M, Cutrera, G, Alaimo, L, Pagliaro   +5 more
openaire   +2 more sources

Predominance of hepatitis C virus genotype 1b in Bulgaria

European Journal of Clinical Microbiology & Infectious Diseases, 1996
A, Andonov, P, Teoharov, S, Bakalova
openaire   +2 more sources

Der Genotyp 1b ist gut behandelbar

CME, 2017
openaire   +1 more source