Results 91 to 100 of about 10,430,018 (295)
Background and Aims: Metabolic profiles are associated with severity of liver histology in chronic hepatitis C (CHC) infection. However, the influence of hepatitis C virus (HCV) genotypes, especially genotype 1 and 2, on the association between metabolic
HSU, CHING-SHENG;LIU, CHEN-HUA;LIU, CHUN-JEN;HSU, SHIH-JER;CHEN, CHI-LING;HWANG, JUEY-JEN;LAI, MING-YANG;CHEN, PEI-JER;CHEN, DING-SHINN;KAO, JIA-HORNG +1 more
core
Vetch (Vicia spp.) is a promising forage legume for Ethiopian livestock systems, but limited information exists on genotype performance across diverse environments. This study evaluated forage yield, quality, and agronomic traits of four vetch genotypes (
Shishay Markos +4 more
doaj +1 more source
Newcastle disease (ND) causes significant economic losses in the poultry industry in developing countries. In Kenya, despite rampant annual ND outbreaks, implementation of control strategies is hampered by a lack of adequate knowledge on the circulating ...
Irene N. Ogali +7 more
doaj +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Background Six nucleotide (nt) insertion in the 5'-noncoding region (NCR) of the nucleoprotein (NP) gene of Newcaslte disease virus (NDV) is considered to be a genetic marker for recent genotypes of NDV, which emerged after 1960.
Hu Shunling +7 more
doaj +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Study of the unknown vine genotype found in Abkhazia
The territory of Abkhazia belongs to the region of origin of the cultivated grapevine. Wild forms, intermediate forms between wild and cultivated grapevines and a variety of local native cultivars grow here.
Ilnitskaya Elena +4 more
doaj +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
A) Workflow depicting erythroid colony (BFU-E) formation genotype/phenotype assay using edited HSPC. HSPC were edited using RNPs targeting the desired region, plated in methocult, and colonies were grown for 14 days.
Yukio Nakamura (39120) +11 more
core +1 more source
Does angiotensin-1 converting enzyme genotype influence motor or cognitive development after pre-term birth? [PDF]
Background Raised activity of the renin-angiotensin system (RAS) may both amplify inflammatory and free radical responses and decrease tissue metabolic efficiency and thus enhance cerebral injury in the preterm infant.
Montgomery, H +23 more
core +1 more source

