Results 111 to 120 of about 10,430,018 (295)

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Combined Factor V Leiden and Prothrombin Genotyping in Patients Presenting With Thromboembolic Episodes

open access: yesArchives of Pathology & Laboratory Medicine, 2001
Abstract Background. —Several genetic defects are associated with increased risk of venous thrombosis. The factor V Leiden (FVL) and prothrombin G20210A mutations are the most frequent causes of inherited thrombophilia. Objectives.
J A, Friedline   +6 more
openaire   +2 more sources

Smouse-et-al_JHered_mixed-assay-genotype-data_DATADRYAD

open access: yes, 2013
Microsatellite genotypes and allele frequencies for datasets described in the paper. Included are genotypes for adult trees; pericarp- and leaf-derived genotypes for seedlings from open patches; and pericarp- and leaf-derived genotypes for seedlings from
Douglas G. Scofield (3311949)   +3 more
core   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Anthocyanin profiles of non-V. vinifera genotypes

open access: yes, 2015
Anthocyanins are the main compounds responsible for the color of red grapes and wine. They play a key role in determining the quality of grape berries. Today, wild Vitis genotypes represent an important source of genetic resistance to biotic and abiotic stresses. In fact, these genotypes are used in breeding programs with V.
Ruocco, S.   +5 more
openaire   +1 more source

Prevalence and genetic diversity of Wolbachia endosymbiont and mtDNA in Palearctic populations of Drosophila melanogaster

open access: yesBMC Evolutionary Biology, 2019
Background Maternally inherited Wolbachia symbionts infect D. melanogaster populations worldwide. Infection rates vary greatly. Genetic diversity of Wolbachia in D.
Roman А. Bykov   +8 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Genotype-guided antiplatelet therapy compared with conventional therapy for patients with acute coronary syndromes: a systematic review and meta-analysis

open access: yes, 2019
To evaluate whether genotype-guided antiplatelet therapy reduces the rates of cardiovascular events and bleeding events in patients with acute coronary syndrome (ACS).
Lukai Zheng (7351619)   +3 more
core   +1 more source

Genotype-by-temperature interactions for life span and its micro-environmental variance in the DGRP.

open access: yes, 2020
Genotype-by-temperature interactions for life span and its micro-environmental variance in the DGRP.
W. Elizabeth Jones (5771492)   +6 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

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