Results 131 to 140 of about 10,430,018 (295)

Comparison of Essential Oil Composition of Flowers of Three Rosa damascena Mill. Genotypes from Kashan

Journal of Medicinal Plants, 2012
Background : Rosa damascena Mill. is one of the most important medicinal and aromatic plants mountainous areas Kashan . This plant have different genotypes that they are very various in size and colour of flowers, number of petals, amount of essential ...
H Batooli, J Safaei-Ghomi
doaj  

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

The Cryptosporidium "mouse" genotype is conserved across geographic areas. [PDF]

, 1999
A 298-bp region of the Cryptosporidium parvum 18S rRNA gene and a 390-bp region of the acetyl coenzyme A synthetase gene were sequenced for a range of Cryptosporidium isolates from wild house mice (Mus domesticus), a bat (Myotus adversus), and cattle ...
Hamilton, S.G., Sturdee, A.P., Thompson, R.C.A., Torres, J., Morgan, U.M., Gracenea, M., Singleton, G., Gomez, M.S., Woodside, D.P.   +8 more
core  

Characterization of drug-resistance mutations in HBV D-genotype chronically infected patients, naïve to antiviral drugs.

, 2011
Presence of drug-resistance mutations in drug-naïve hepatitis B virus (HBV) infected patients can seriously compromise response to antiviral treatment.
V. Svicher, Sarrecchia, C, Gori, C, BERTOLI, ADA, Salpini, R, C. Gori, Bertoli, A, PERNO, CARLO FEDERICO, F. Scopelliti, T. Cappiello, Cento, V, De Sanctis, GM, A. Spanò, G.M. De Sanctis, A. Bertoli, Micheli, V, V. Cento, SARRECCHIA, CESARE, R. Salpini, Rizzardini, G, C. Sarrecchia, Svicher, V, Scopelliti, F, Perno, CF, Cappiello, T, G. Rizzardini, Angelico, M, C.F. Perno, V. Micheli, Spanò, A, ANGELICO, MARIO, M. Angelico   +31 more
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Virulence and Cross-Protection Conferred by an Attenuated Genotype I-Based Chimeric Japanese Encephalitis Virus Strain Harboring the E Protein of Genotype V in Mice. [PDF]

Microbiol Spectr, 2022
Xia Q, Zhang Y, Yang Y, Ma X, Guan Z, Zhang J, Li Z, Liu K, Li B, Shao D, Qiu Y, Wei J, Ma Z.   +12 more
europepmc   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Investigation of Cryptosporidium infection in a broad range of hosts in northern China

Parasites & Vectors
Background Cryptosporidium infection occurs in humans, domestic animals, and wildlife. To date, at least 49 species and 120 genotypes have been identified. Hitherto, molecular identification of Cryptosporidium species in wildlife has seldom been reported
Ziheng Liu, Jing Yang, Jiushikun Juman, Nannan Cui, Ligu Mi, Sándor Hornok, Guoyu Zhao, Quan Liu, Yuanzhi Wang   +8 more
doaj   +1 more source

Origin and Spread of the Dengue Virus Type 1, Genotype V in Senegal, 2015-2019. [PDF]

Viruses, 2021
Dieng I, Cunha M, Diagne MM, Sembène PM, Zanotto PMA, Faye O, Faye O, Sall AA.   +7 more
europepmc   +1 more source