Results 41 to 50 of about 141,362 (266)

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna   +16 more
wiley   +1 more source

Prevalence of colonization and mitochondrial large subunit rRNA mutation of Pneumocystis jiroveci among Iranian children

open access: yesIranian Journal of Microbiology, 2016
Background and Objectives: Pneumocystis jiroveci is an important causative agent of Pneumocystis pneumonia. During childhood, exposure to Pneumocystis occurs and antibody was built in early childhood.
Parisa Badiee   +4 more
doaj  

Secretory Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized for Vaso‐Occlusive Pain Episodes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman   +10 more
wiley   +1 more source

EVALUATION OF DIFFERENT BREAD WHEAT LINES IN THE F6 AND F7 GENERATION FOR GRAIN YIELD AND ITS ATTRIBUTES [PDF]

open access: yesJournal of Plant Production, 2000
This investigation was carried out to evaluate 66 wheat lines derived from five crosses of bread wheat along with their seven parents and ten check cultivars giving a total of 83 genotypes. The 66 lines were evaluated in the F6 and F7 generations in 1995/
Afaf Tolba,
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Parallel Detection of the Unamplified Carbapenem Resistance Genes blaNDM-1 and blaOXA-1 Using a Plasmonic Nano-Biosensor with a Field-Portable DNA Extraction Method

open access: yesBiosensors
Antimicrobial resistance (AMR) is a rapidly growing global concern resulting from the overuse of antibiotics in agricultural and clinical settings.
Kaily Kao, Evangelyn C. Alocilja
doaj   +1 more source

PHENOTYPIC AND GENOTYPIC DETECTION OF METHICILLIN- RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) IN BROILER CHICKENS [PDF]

open access: yesAssiut Veterinary Medical Journal, 2014
Methicillin-resistant Staphylococcus aureus (MRSA) has been increasingly reported as emerging problem in veterinary medicine, particularly in small animals and poultry. In Egypt, there is limited information on MRSA carriage in poultry.
AML A.M. BAKEET, SAMAH F. DARWISH
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Genotyping with TaqMAMA

open access: yesGenomics, 2004
TaqMAMA combines the quantitative strengths of TaqMan with the allele-specific PCR of MAMA. In this article we develop TaqMAMA as a technique for screening human DNA samples for known genetic polymorphisms. In the first set of experiments, plasmids that model all types of genetic polymorphisms were used to understand the relationship between TaqMAMA ...
Baohui, Li   +3 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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