Results 41 to 50 of about 189,911 (267)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

High proportion of tuberculosis recent transmission in rural areas of Northeastern China: a 3-year prospective population-based genotypic and spatial analysis in Hinggan League, China

Microbiology Spectrum
Tuberculosis (TB) remains a significant public health challenge in China, particularly in rural areas like Hinggan League (HL), Inner Mongolia. Understanding the genetic diversity and transmission dynamics of Mycobacterium tuberculosis (MTB) strains is ...
Xichao Ou, Xiangchen Li, Shaojun Pei, Bing Zhao, Liping Feng, Chong Teng, Yewei Lu, Hanfang Zhu, Yang Zhou, Hui Xia, Zhengwei Liu, Xiaomeng Wang, Yanling Wang, Richard Anthony, Yanlin Zhao   +14 more
doaj   +1 more source

PHENOTYPIC AND GENOTYPIC DETECTION OF METHICILLIN- RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) IN BROILER CHICKENS [PDF]

Assiut Veterinary Medical Journal, 2014
Methicillin-resistant Staphylococcus aureus (MRSA) has been increasingly reported as emerging problem in veterinary medicine, particularly in small animals and poultry. In Egypt, there is limited information on MRSA carriage in poultry.
AML A.M. BAKEET, SAMAH F. DARWISH
doaj   +1 more source

Genotypic fidelity of LCL.

, 2013
Genotypic fidelity is shown as mean pairwise distances among 19 paired comparisons of LCL and PBMC genotypes, for increasingly stringent SNP filtering by population call rate. A) Genotypic fidelity between LCL and PBMC source DNA from the same individual,
Joseph B. Margolick (255437), James I. Mullins (30582), Geoffrey S. Gottlieb (235246), Lisa P. Jacobson (255443), Charles R. Rinaldo (235434), Joshua T. Herbeck (214670), Roger Detels (255434), John P. Phair (370682), Kim Wong (262770)   +8 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Prevalence of colonization and mitochondrial large subunit rRNA mutation of Pneumocystis jiroveci among Iranian children

Iranian Journal of Microbiology, 2016
Background and Objectives: Pneumocystis jiroveci is an important causative agent of Pneumocystis pneumonia. During childhood, exposure to Pneumocystis occurs and antibody was built in early childhood.
Parisa Badiee, Ali Rezapour, Amin Abbasian, Hamid Reza Foroutan, Hadis Jafarian   +4 more
doaj  

Phenotypic and genotypic data data

, 2023
Phenotypic and genotypic ...
Paterne AGRE (13848226)
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Genotypic variation in the ability of wheat roots to penetrate wax layers

, 2013
The role of the root system in mediating crop yields has recently been emphasised, resulting in several laboratory approaches for phenotyping root traits.
Davies, W. J., Webster, C. P., White, R. P., Andralojc, P. J., Watts, C. W., Phillips, A. L., Whalley, W. R., Parry, M. A. J., Andralojc, J., Dodd, I. C., White, Robin P.   +10 more
core   +1 more source