Results 61 to 70 of about 214,572 (265)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Assessing Phenotypic and Genotypic Resistance to Flumethrin in Varroa destructor Populations in Muğla, Türkiye

Insects
Beekeepers use a variety of methods to control Varroa destructor (varroa). Chemical control relies heavily on flumethrin, amitraz, coumaphos, and tau-fluvalinate products.
Ali Sorucu, Bekir Çöl, Esra Dibek, Anara Babayeva   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Early phase of effective treatment induces distinct transcriptional changes in Mycobacterium tuberculosis expelled by pulmonary tuberculosis patients

Scientific Reports, 2021
Effective treatment reduces a tuberculosis patient's ability to infect others even before they test negative in sputum or culture. Currently, the basis of reduced infectiousness of the Mycobacterium tuberculosis (Mtb) with effective treatment is unclear.
Ambreen Shaikh, Kalpana Sriraman, Smriti Vaswani, Vikas Oswal, Sudha Rao, Nerges Mistry   +5 more
doaj   +1 more source

APOC3 genotypic and allelic frequencies.

, 2012
APOC3 genotypic and allelic frequencies.
Debora Mecikovsky (147842), Carlos A. Rocco (147835), Paula Aulicino (147850), Andrea Mangano (147875), Rosa Bologna (147860), Luisa Sen (147867)   +5 more
core   +1 more source

Genotypic data associated with the GWAS analysis

, 2023
Here is the genotypic data associated with the GWAS study 
Paterne AGRE (13848226)
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Individual genotypic data

, 2015
Individual genotypic data for 180 samples scored at 15,123 SNP ...
Waters, Jonathan M, Jonathan M Waters (3298848), Dussex, Nicolas, Chuah, Aaron, Nicolas Dussex (696163), Aaron Chuah (739671)   +5 more
core   +1 more source

Malaria prevalence among G6PD genotypic variants.

, 2021
A) Prevalence of individual G6PD genotypic variants and their corresponding malaria prevalence. B) Specificity and Sensitivity of detecting malaria infection among the different G6PD genotypic variants using ROC.
Sherifa Annan (11485673), George Adu Asumah (11485676), Alexander Asamoah (5520254), Abena Busayo (11485670), Kwame Kumi Asare (11485667), Dorcas Bredu (9018752), Keziah Laurencia Malm (9344757), Joana Abankwa (3418715), Linda Eva Amoah (9344739), Donu Dickson (9344745), Nana Yaw Peprah (4804200)   +10 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source