Results 61 to 70 of about 189,911 (267)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The genotypic table.

open access: yes, 2014
The genotypic table.
Ruijie Zhang (194261)   +9 more
core   +1 more source

Malaria prevalence among G6PD genotypic variants.

open access: yes, 2021
A) Prevalence of individual G6PD genotypic variants and their corresponding malaria prevalence. B) Specificity and Sensitivity of detecting malaria infection among the different G6PD genotypic variants using ROC.
Sherifa Annan (11485673)   +10 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Transformation of QTL genotypic effects to allelic effects [PDF]

open access: yes, 2005
The genotypic and allelic effect models are equivalent in terms of QTL detection in a simple additive model, but the QTL allelic model has the advantage of providing direct information for marker-assisted selection.
Yoshitaka Nagamine, Nagamine Yoshitaka
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Genetic and Biologic Characterization of Some Olive (O/ea europaea L.) Cultivars Grown in Turkey

open access: yesJournal of Agricultural Sciences, 2004
There are many olive (O/ea europaea L.) varieties grown in Anatolia, vvhich have not been characterized (morphologic and biologic characteristics), yet. Some of them that have been identified by morphologic and biological characteristics, but stili have ...
Mücahit Taha Ozkaya
doaj   +1 more source

Significant genotypic associations detected.

open access: yes, 2016
Significant genotypic associations detected.
Ana M. Zubiaga (429975)   +7 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Exploiting phenotypic and genotypic diversity against colletotrichum truncatum in chilli hybrids developed using resistant breeding lines

open access: yes
In an effort to control anthracnose disease, one of the major problems that has been faced by farmers, 14 chilli hybrids and their parents were screened phenotypically using the fruit inoculation method under laboratory conditions. Genotypic screening of
Jaafar, Juju Nakasha   +4 more
core   +1 more source

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