Results 151 to 160 of about 131,669 (291)

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

open access: yesAdvanced Science, EarlyView.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li   +19 more
wiley   +1 more source

Analysis of Morphologically Similar Staphylococcus aureus Colonies for Assessment of Phenotypic and Genotypic Correlation. [PDF]

open access: yesJ Clin Microbiol, 2017
Totten M   +5 more
europepmc   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

open access: yesAdvanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva   +28 more
wiley   +1 more source

الارتباط وتحليل معامل المسار في حنطة الخبز [PDF]

open access: yesمجلة ابحاث كلية التربية الاساسية, 2010
استخدمت ستة أصناف من حنطة الخبز وهجنها التبادلية النصفية في تجربة بتصميم القطاعات العشوائية الكاملة بأربعة مكررات لحساب معامل الارتباط الظاهري والوراثي بين أزواج الصفات: حاصل الحبوب وعدد السنابل في النبات وطول السنبلة وعدد الحبوب بالسنبلة ووزن 100حبة ...
doaj  

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

open access: yesAdvanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv   +8 more
wiley   +1 more source

Genotypic values and genetic correlations for components and oil content of bunch of hybrids between caiaué and dendê

open access: diamond, 2021
A. F. de Freitas   +5 more
openalex   +2 more sources

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

open access: yesAdvanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li   +12 more
wiley   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

open access: yesAdvanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen   +31 more
wiley   +1 more source

Home - About - Disclaimer - Privacy