Results 51 to 60 of about 131,669 (291)

Korelasi Genotipik antara Hasil dengan Tingkat Ketahanan terhadap Penyakit Bercak Daun Hitam pada Kacang Tanah [PDF]

open access: yes, 1998
A field evaluation was conducted to study the genotypic correlation between yield potentials and resistance level to the late leafspot of peanut. The experiment was carried out at Muara experimental-field from October 1994 to January 1995 using 100 ...
Hadi, S. (S)   +5 more
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

COMPARATIVE ASESSMENT OF BACTERIAL EXCRECTION DEGREE DEPENDING FROM SENSIVITY PROFILE OF MYCOBACTERIUM TUBERCULOSIS TO ANTITUBERCULOSIS DRUGS [PDF]

open access: yesAnnals of Mechnikov's Institute, 2018
One of the important part of the epidemiological component of tuberculosis pathomorphosis in modern conditions is the change in important biological properties of the pathogen, not only in the form of increased frequency and extension of Mycobacterium ...
Schevchenko O.S., Hovardovska O.O.
doaj   +1 more source

Mismatches between the genetic and phenotypic sex in the wild Kou population of Nile tilapia Oreochromis niloticus [PDF]

open access: yes, 2019
Sex determination and sex chromosomes can be very diverse between teleost species. The group of tilapias shows a polymorphism in sex determination not only between closely related species but also between domestic strains within a species.
Baroiller, Jean-François   +3 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Exploitation of the Genetic Variability of Diverse Metric Traits of Durum Wheat (Triticum turgidum L. ssp. durum Desf.) Cultivars for Local Adaptation to Semi-Arid Regions of Algeria

open access: yesPlants
Abiotic stresses pose significant challenges to wheat farming, yet exploiting the genetic variability within germplasm collections offers an opportunity to effectively address these challenges.
Zine El Abidine Fellahi   +7 more
doaj   +1 more source

Estimates of genetic parameters for fruit yield and quality in custard apple progenies Estimativas de parâmetros genéticos do rendimento e da qualidade do fruto de progênies da pinheira

open access: yesRevista Brasileira de Fruticultura, 2007
Apparently, there are no custard apple cultivars defined for the northeastern region of Brazil. The establishment of breeding programs aimed at the selection of types from productive locations for later cloning is desirable.
Paulo Sérgio Lima e Silva   +5 more
doaj   +1 more source

Impact of three ampicillin dosage regimens on selection of ampicillin resistance in Enterobacteriaceae and excretion of blaTEM genes in swine feces [PDF]

open access: yes, 2007
The aim of this study was to assess the impact of three ampicillin dosage regimens on ampicillin resistance among Enterobacteriaceae recovered from swine feces using phenotypic and genotypic approaches.
Bibbal, Delphine   +6 more
core   +5 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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