Results 1 to 10 of about 1,163,135 (344)
Pharmaceutics, 2021 Anthracyclines are among the most used chemotherapeutic agents in breast cancer (BC). However their use is hampered by anthracycline-induced cardiotoxicity (AIC).
Alejandro Velasco-Ruiz +14 more
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Pharmaceutics, 2023 The implementation of pharmacogenetics (PGx) is a main milestones of precision medicine nowadays in order to achieve safer and more effective therapies. Nevertheless, the implementation of PGx diagnostics is extremely slow and unequal worldwide, in part ...
Rocio Nunez-Torres +10 more
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mBio, 2023 Wastewater-based epidemiology is a powerful tool for monitoring the emergence and spread of viral pathogens at the population scale. Typical polymerase chain reaction (PCR)-based methods of quantitative and genomic monitoring of viruses in wastewater ...
Harry T. Child +13 more
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Cellsnp-lite: an efficient tool for genotyping single cells
bioRxiv, 2021 Summary Single-cell sequencing is an increasingly used technology and has promising applications in basic research and clinical translations. However, genotyping methods developed for bulk sequencing data have not been well adapted for single-cell data ...
Xianjie Huang, Yuanhua Huang
semanticscholar +1 more source
A crowdsourcing database for the copy-number variation of the Spanish population
Human Genomics, 2023 Background Despite being a very common type of genetic variation, the distribution of copy-number variations (CNVs) in the population is still poorly understood.
Daniel López-López +13 more
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Scientific Reports, 2022 Only up to 25% of the cases in which there is a familial aggregation of breast and/or ovarian cancer are explained by germline mutations in the well-known BRCA1 and BRCA2 high-risk genes.
B. Benito-Sánchez +11 more
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Frontiers in Plant Science, 2022 Identification of peanut cultivars for distinct phenotypic or genotypic traits whether using visual characterization or laboratory analysis requires substantial expertise, time, and resources.
William Z. Payne +8 more
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A framework for variation discovery and genotyping using next-generation DNA sequencing data
Nature Genetics, 2011 Recent advances in sequencing technology make it possible to comprehensively catalog genetic variation in population samples, creating a foundation for understanding human disease, ancestry and evolution.
M. DePristo +17 more
semanticscholar +1 more source
mBio, 2014 Rapidly fatal cases of invasive fungal infections due to a fungus later identified as Saprochaete clavata were reported in France in May 2012. The objectives of this study were to determine the clonal relatedness of the isolates and to investigate ...
Sophie Vaux +8 more
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A Robust, Simple Genotyping-by-Sequencing (GBS) Approach for High Diversity Species
PLoS ONE, 2011 Advances in next generation technologies have driven the costs of DNA sequencing down to the point that genotyping-by-sequencing (GBS) is now feasible for high diversity, large genome species.
Robert J. Elshire +6 more
semanticscholar +1 more source