Results 121 to 130 of about 1,163,135 (344)

tGBS® genotyping-by-sequencing enables reliable genotyping of heterozygous loci

Nucleic Acids Research, 2017
Conventional genotyping-by-sequencing (cGBS) strategies suffer from high rates of missing data and genotyping errors, particularly at heterozygous sites.
Alina Ott, Sanzhen Liu, James c. Schnable, C. Yeh, Kai Wang, P. Schnable   +5 more
semanticscholar   +1 more source

Genotype [PDF]

, 2011
Martin Hahn, Rohan Palmer
openaire   +2 more sources

The number of PON1 mutant alleles, but not PON1 phenotype, is associated with Gensini score of coronary damage

Romanian Journal of Laboratory Medicine, 2013
Obiective. Scopul acestui studiu a fost de a examina efectele polimorfismelor (SNPs) genei PON1 la nivelul regiunii promotor (-909 şi -832) şi a primului exon (+575, 20352A>G, rezultând substituirea Q192R) asupra activităţilor paraoxonazei-1 (PON1) într ...
Ilea Irina, Lupan Iulia, Leucuta Daniel Corneliu, Duncea Caius Romulus, Dronca Maria   +4 more
doaj   +1 more source

Nucleotide sequencing and DNA polymorphism studies of beta-lactoglobulin gene in native Saudi goat breeds in relation to milk yield

Czech Journal of Animal Science, 2015
β-Lactoglobulin (β-LG) is the dominant non-casein whey protein found in milk of bovine and of most ruminants. The amino acid sequence of β-LG along with its 3-dimensional structure illustrates linkage with the lipocalin superfamily.
A.A.M. El Hanafy, M.I. Qureshi, J. Sabir, M. Mutawakil, M.M.M. Ahmed, H. El Ashmaoui, H.A.M.I. Ramadan, M. Abou-Alsoud, M.A. Sadek   +8 more
doaj   +1 more source

Two Examples of the -D-/-D- Genotype in an American Family [PDF]

, 1953
R. K. Waller, Ruth Sanger, O. B. Bobbitt
openalex   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

A Specific Abnormality Associated with a Variety of Genotypes [PDF]

, 1944
L. C. Dunn, S. Gluecksohn‐Schoenheimer
openalex   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Phenotypes, Genotypes and Gens [PDF]

, 1912
O. F. Cook
openalex   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source