Results 151 to 160 of about 554,185 (237)

Machine learning solutions for integrating partially overlapping genetic datasets and modelling host-endophyte effects in ryegrass (<i>Lolium</i>) dry matter yield estimation. [PDF]

Front Plant Sci
Zhu J, Malmberg MM, Shinozuka M, Retegan RM, Cogan NO, Jacobs JL, Giri K, Smith KF.   +7 more
europepmc   +1 more source

PP1A Modulates the Efficacy of Lenvatinib Plus ICIs Therapy by Inhibiting Ferroptosis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
PP1A dephosphorylates Keap1 at the S104 site, stabilizing and promoting the nuclear translocation of Nrf2, which upregulates the expression of antioxidant genes and PD‐L1. This leads to suppressed ferroptosis and enhanced immune evasion, thereby improving the efficacy of TKI and ICI combination therapy.
Jitong Zhou, Meng Gao, Shikun Zhang, Wing‐Wa Guo, Wenzhi He, Minghe Zhang, Xi Chen, Cairang Dongzhi, Xiaomian Li, Yufeng Yuan, Weijie Ma   +10 more
wiley   +1 more source

Graphical pangenomics-enabled characterization of structural variant impact on gene expression in Brassica napus. [PDF]

Theor Appl Genet
Yildiz G, Zanini SF, Weber S, Kopalli V, Kox T, Abbadi A, Snowdon RJ, Golicz AA.   +7 more
europepmc   +1 more source

The SlDOF9‐SlSWEET17 Module: a Switch for Controlling Sugar Distribution Between Nematode Induced Galls and Roots in Tomato

Advanced Science, EarlyView.
Root‐knot nematode (RKN) disease seriously affects the yield and quality of vegetable crops. SlDOF9‐SlSWEET17 model helps plants resist RKN infection during early stage by switching off the sugar transport capacity of other SlSWEET proteins that are hijacked by RKNs.
Xiaoyun Wang, Zhimei Wang, Xinyue Tang, Jiamei Qin, Xiaoxuan Zhou, Lixia Gu, Huihui Bian, Lulu Sun, Huang Huang, Rui Yang, Jianli Wang, Shaohui Wang, Shuangchen Chen, Zhongren Yang, Wenchao Zhao   +14 more
wiley   +1 more source

Genetic Epidemiology and Resistance Investigations of Clinical Yeasts in Alexandria, Egypt. [PDF]

Pathogens
Spruijtenburg B, Melchior do Prado C, Kempen MV, Shawky SM, Meis JF, Aparecida Vicente V, Queiroz-Telles F, Groot T, El-Kholy MA, Meijer EFJ.   +9 more
europepmc   +1 more source

Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis

Advanced Science, EarlyView.
Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo, Yan Wang, Qiudi Liu, Zhaoyang Luo, Xiaomu Tian, Yuquan Wang, Yang Liu, Zhiwei Ning, Yingying Guo, Huiying Gao, Xinyue Wang, Jinglong Feng, Mengmeng Liu, Dina Saifullina, Yixin Zhang, Tengfei Pan, Yu Bian, Tao Ban, Tianyu Li, Yunyan Gu, Haihai Liang   +20 more
wiley   +1 more source

Integrating <i>RHD</i> Genotyping for More Accurate Rh(D) Antigen Phenotyping: A Retrospective Study. [PDF]

Medicina (Kaunas)
Barouqa M, Dela Cruz N.
europepmc   +1 more source

Genotype × environment interactions [PDF]

Genetics Selection Evolution, 1972
openaire   +4 more sources

Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein

Advanced Science, EarlyView.
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren, Pengfei Fan, Xinghai Zhang, Ting Fang, Zhengshan Chen, Yanfeng Yao, Xiangyang Chi, Guanying Zhang, Xiaofan Zhao, Bingjie Sun, Fangxu Li, Zixuan Liu, Zhenwei Song, Baoyue Zhang, Cheng Peng, Entao Li, Yilong Yang, Jianmin Li, Sandra Chiu, Changming Yu   +19 more
wiley   +1 more source

Virome capture sequencing for comprehensive HPV genotyping in cervical samples. [PDF]

Sci Prog
Sasivimolrattana T, Liewchalermwong S, Chantratita W, Sensorn I, Chaiwongkot A, Bhattarakosol P.   +5 more
europepmc   +1 more source