, 2014 Large case/control Genome-Wide Association Studies (GWAS) often include groups of related individuals with known relationships. When testing for associations at a given locus, current methods incorporate only the familial relationships between ...
Li, Peng +3 more
core +1 more source
Low genetic variability, female-biased dispersal and high movement rates in an urban population of Eurasian badgersMeles meles [PDF]
, 2008 1. Urban and rural populations of animals can differ in their behaviour, both in order to meet their ecological requirements and due to the constraints imposed by different environments.
Bijlsma +66 more
core +2 more sources
Evaluation of TypeSeq, a Novel High-Throughput, Low-Cost, Next-Generation Sequencing-Based Assay for Detection of 51 Human Papillomavirus Genotypes. [PDF]
, 2019 BackgroundHuman papillomaviruses (HPV) cause over 500 000 cervical cancers each year, most of which occur in low-resource settings. Human papillomavirus genotyping is important to study natural history and vaccine efficacy. We evaluated TypeSeq, a novel,
Boland, Joseph +20 more
core +1 more source
Multiple Locus Variable number of tandem repeat Analysis : a molecular genotyping tool for Paenibacillus larvae [PDF]
, 2016 American Foulbrood, caused by Paenibacillus larvae, is the most severe bacterial disease of honey bees (Apis mellifera). To perform genotyping of P.larvae in an epidemiological context, there is a need of a fast and cheap method with a high resolution ...
Alippi +40 more
core +2 more sources
Using GWAS Data to Identify Copy Number Variants Contributing to Common Complex Diseases
, 2010 Copy number variants (CNVs) account for more polymorphic base pairs in the human genome than do single nucleotide polymorphisms (SNPs). CNVs encompass genes as well as noncoding DNA, making these polymorphisms good candidates for functional variation ...
Teslovich, Tanya M., Zöllner, Sebastian
core +1 more source
Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites. [PDF]
, 2007 BACKGROUND: Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudescence, or reinfection.
Anderson, T J C +14 more
core +2 more sources
Human streptococcus agalactiae strains in aquatic mammals and fish [PDF]
, 2013 <p>Background: In humans, Streptococcus agalactiae or group B streptococcus (GBS) is a frequent coloniser of the rectovaginal tract, a major cause of neonatal infectious disease and an emerging cause of disease in non-pregnant adults.
Crumlish, M. +7 more
core +5 more sources
Discriminatory ability of hypervariable variable number tandem repeat loci in population-based analysis of Mycobacterium tuberculosis strains, London, UK [PDF]
, 2009 To address conflicting results about the stability of variable number tandem repeat (VNTR) loci and their value in prospective molecular epidemiology of Mycobacterium tuberculosis, we conducted a large prospective population-based analysis of all M ...
Brown, T +3 more
core +3 more sources
CGIAR Excellence in Breeding Platform - Plan of Work and Budget 2020 [PDF]
, 2020 At the end of 2019, all CGIAR centers had submitted improvement plans based on an EiB template and in close collaboration with EiB staff while – in a parallel process with breeding programs, funders and private sector representatives – a vision for ...
CGIAR Excellence in Breeding Platform
core
Whole genome sequencing and microsatellite analysis of the Plasmodium falciparum E5 NF54 strain show that the var, rifin and stevor gene families follow Mendelian inheritance [PDF]
, 2018 Background: Plasmodium falciparum exhibits a high degree of inter-isolate genetic diversity in its variant surface antigen (VSA) families: P. falciparum erythrocyte membrane protein 1, repetitive interspersed family (RIFIN) and subtelomeric variable ...
Bruske, Ellen +2 more
core +5 more sources