Results 31 to 40 of about 783,438 (323)

Germline pathogenic variants of 11 breast cancer genes in 7,051 Japanese patients and 11,241 controls

Nature Communications, 2018
Association between variants in 11 different genes and breast cancer risk has been established and sequencing of these genes is recommended to provide personalized diagnosis, therapy, and surveillance for the high-risk patients and their relatives.
Yukihide Momozawa, Yusuke Iwasaki, Michael T. Parsons, Yoichiro Kamatani, Atsushi Takahashi, Chieko Tamura, Toyomasa Katagiri, Teruhiko Yoshida, Seigo Nakamura, Kokichi Sugano, Yoshio Miki, Makoto Hirata, Koichi Matsuda, Amanda B. Spurdle, Michiaki Kubo   +14 more
doaj   +1 more source

PCR Based Genotyping of Lulu Cattle of Nepal for A1, A2 Type Beta-caseins [PDF]

, 2020
Lulu is an indigenous breed of cattle (Bos taurus) found in high altitude regions of western Nepal. Population of Lulu cattle has been declining due to introgression with other exotic breeds to increase milk productivity.
Budhathoki, N. (Nabina), GC, S. (Sudarshan), Gorkhali, N. A. (Neena), Lama, S. (Srijana), Pokharel, P. (Prashanna), Pokhrel, B. R. (Bhoj), Sapkota, S. (Saroj), Sherpa, C. (Chhiring)   +7 more
core  

The genetic basis of host preference and resting behavior in the major African malaria vector, Anopheles arabiensis [PDF]

, 2016
Malaria transmission is dependent on the propensity of Anopheles mosquitoes to bite humans (anthropophily) instead of other dead end hosts. Recent increases in the usage of Long Lasting Insecticide Treated Nets (LLINs) in Africa have been associated ...
Collier, T. J., Cornel, A.J., Eskin, E., Ferguson, H.M., Govella, N. J., Kang, E.Y., Kihonda, A., Kreppel, K.S., Lanzaro, G.C., Lee, Y., Main, B. J., Nieman, C.C., Weakley, A.M.   +12 more
core   +3 more sources

Programmatic Access to FAIRified Digital Plant Genetic Resources

Journal of Integrative Bioinformatics, 2020
Genetic variance within the genotype of population and its mapping to phenotype variance in a systematic and high throughput manner is of interest for biodiversity and breeding research.
Ghaffar Mehmood, Schüler Danuta, König Patrick, Arend Daniel, Junker Astrid, Scholz Uwe, Lange Matthias   +6 more
doaj   +1 more source

Assessing the genetic diversity of rice originating from Bangladesh, Assam and West Bengal [PDF]

, 2015
Acknowledgements This work was funded by BBSRC research project BB/J00336/1. FS and a part of the proportion of the cost of the Illumina genotyping was funded by a Beachell-Borlag International Fellowship.
Dasgupta, Tapash, Datta, Sutapa, Hedley, Peter E., Islam, M. Rafiqul, Macaulay, Malcolm, McNally, Kenneth L., Norton, Gareth J., Price, Adam H., Sarma, Ramendra, Savio, Filipe L., Sumon, Mahmud H., Travis, Anthony J.   +11 more
core   +2 more sources

Listeriosis: genotyping as a key for identification a possible source of infection [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2019
Objective. To perform a comparative analysis of clinical and food isolates of Listeria monocytogenes collected in the European part of Russia in 2018–2019. Materials and Methods.
Voronina O.L., Kunda M.S., Ryzhova N.N., Kutuzova A.V., Aksenova E.I., Karpova T.I., Tartakovskij I.S., Yushchuk N.D., Klimova E.A., Karetkina G.N., Chemeris O.Yu., Gruzdeva O.A., Melkumyan A.R., Orlova O.E., Burmistrova E.N.   +14 more
doaj   +1 more source

Feasibility of High-Throughput Genome-Wide Genotyping using DNA from Stored Buccal Cell Samples

Biomarker Insights, 2010
It is unclear if buccal cell samples contain sufficient human DNA with adequately sized fragments for high throughput genetic bioassays. Yet buccal cell sample collection is an attractive alternative to gathering blood samples for genetic epidemiologists
Stephanie J. Loomis, Lana M. Olson, Louis R. Pasquale, Janey Wiggs, Daniel Mirel, Andrew Crenshaw, Melissa Parkin, Brandon Rahhal, Stephanie Tetreault, Peter Kraft, Shelley S. Tworoger, Jonathan L. Haines, Jae H. Kang   +12 more
doaj   +1 more source

Peculiarities of polymorphism of Helicobacter pylori virulence genes and IL-1 genes in peptic ulcer of stomach and duodenum, associated with Helicobacter pylori

Бюллетень сибирской медицины, 2005
The prevalence of H.pylori virulence genes (iceA, cagA, babA2, vacA) as well as the distribution of the IL-1 genes was studied in patients with H.pylori-associated gastric and duodenal ulcer disease.
O. A. Tchernova, E. R. Nasybullina, O. V. Gorshkov, G. F. Shaimardanova, V. M. Tchernov, R. A. Abdulkhakov   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source