Results 31 to 40 of about 181,932 (222)
Annals of Agricultural and Environmental Medicine, 2015 Introduction During 2008–2012, a total of 466 ticks Ixodes ricinus removed from humans were collected and tested for the presence of Borrelia burgdorferi sensu lato (Bbsl).
Ondřej Bonczek +3 more
doaj +1 more source
Feasibility of High-Throughput Genome-Wide Genotyping using DNA from Stored Buccal Cell Samples
Biomarker Insights, 2010 It is unclear if buccal cell samples contain sufficient human DNA with adequately sized fragments for high throughput genetic bioassays. Yet buccal cell sample collection is an attractive alternative to gathering blood samples for genetic epidemiologists
Stephanie J. Loomis +12 more
doaj +1 more source
Differentiation of Tuberculosis Strains in a Population with Mainly Beijing-family Strains
Emerging Infectious Diseases, 2006 A high prevalence of tuberculosis (TB) isolates that are genetically homogenous and from the Beijing family has been reported in Russia. To map TB transmission caused by these strains, new genotyping systems are needed.
Vladyslav Nikolayevskyy +5 more
doaj +1 more source
mSystems, 2021 Q (query) fever is an infectious zoonotic disease caused by the Gram-negative bacterium Coxiella burnetii. Although the disease has been studied for decades, it still represents a threat due to sporadic outbreaks across farms in Europe.
Akinyemi M. Fasemore +6 more
doaj +1 more source
Analysis of Genotype-Phenotype Association using Genomic Informational Field Theory (GIFT) [PDF]
arXiv, 2022 We show how field- and information theory can be used to quantify the relationship between genotype and phenotype in cases where phenotype is a continuous variable. Given a sample population of phenotype measurements, from various known genotypes, we show how the ordering of phenotype data can lead to quantification of the effect of genotype.
arxiv
Density behavior of spatial birth-and-death stochastic evolution of mutating genotypes under selection rates [PDF]
Russian Journal of Mathematical Physics, 2014, 21 (4), p. 450-459, 2013 We consider birth-and-death stochastic evolution of genotypes with different lengths. The genotypes might mutate that provides a stochastic changing of lengthes by a free diffusion law. The birth and death rates are length dependent which corresponds to a selection effect.
arxiv +1 more source
Molecular Oncology, EarlyView.Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou +11 more
wiley +1 more source
CYP2D7 sequence variation interferes with TaqMan CYP2D6*15 and *35 genotyping
Frontiers in Pharmacology, 2016 TaqMan™ genotyping assays are widely used to genotype CYP2D6, which encodes a major drug metabolizing enzyme. Assay design for CYP2D6 can be challenging owing to the presence of two pseudogenes, CYP2D7 and CYP2D8, structural and copy number variation and
Amanda K Riffel +10 more
doaj +1 more source
Microorganisms, 2020 In recent decades, the incidence and prevalence of nontuberculous mycobacteria (NTM) have greatly increased, becoming a major worldwide public health problem.
Jeong-Ih Shin +2 more
doaj +1 more source
Phenotype Search Trajectory Networks for Linear Genetic Programming [PDF]
arXiv, 2022 Genotype-to-phenotype mappings translate genotypic variations such as mutations into phenotypic changes. Neutrality is the observation that some mutations do not lead to phenotypic changes. Studying the search trajectories in genotypic and phenotypic spaces, especially through neutral mutations, helps us to better understand the progression of ...
arxiv