Genotyping Techniques to Address Diversity in Tumors [PDF]
Array-based genotyping platforms have during recent years been established as a valuable tool for the characterization of genomic alterations in cancer. The analysis of tumor samples, however, presents challenges for data analysis and interpretation.
Lindgren, David+2 more
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Liquid biopsy genotyping in lung cancer: ready for clinical utility? [PDF]
Liquid biopsy is a blood test that detects evidence of cancer cells or tumor DNA in the circulation. Despite complicated collection methods and the requirement for technique-dependent platforms, it has generated substantial interest due, in part, to its ...
Chen, Yi-Lin+7 more
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A Novel Genome-Wide Association Study Approach Using Genotyping by Exome Sequencing Leads to the Identification of a Primary Open Angle Glaucoma Associated Inversion Disrupting ADAMTS17 [PDF]
Closed breeding populations in the dog in conjunction with advances in gene mapping and sequencing techniques facilitate mapping of autosomal recessive diseases and identification of novel disease-causing variants, often using unorthodox experimental ...
A McKenna+27 more
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Quality of DNA extracted from formalin-fixed, paraffin-embedded canine tissues. [PDF]
Veterinary pathology tissue banks are valuable resources for genetic studies. However, limited data exist as to whether quality DNA can be extracted from these tissues for use in canine genotyping studies.
Bannasch, Danika L+2 more
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Efficient techniques for genotype‐phenotype correlational analysis [PDF]
Abstract Background Single Nucleotide Polymorphisms (SNPs) are sequence variations found in individuals at some specific points in the genomic sequence. As SNPs are highly conserved throughout evolution and within a population, the map of SNPs serves as an excellent genotypic marker.
Sudipta Pathak+3 more
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An integrated molecular and conventional breeding scheme for enhancing genetic gain in maize in Africa [PDF]
Open Access Journal; Published online: 06 Nov 2019Maize production in West and Central Africa (WCA) is constrained by a wide range of interacting stresses that keep productivity below potential yields.
Gedil, M., Menkir, A.
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Evaluation of Cryptosporidium parvum Genotyping Techniques [PDF]
ABSTRACT We evaluated the specificity and sensitivity of 11 previously described species differentiation and genotyping PCR protocols for detection of Cryptosporidium parasites. Genomic DNA from three species of Cryptosporidium parasites (genotype 1 and genotype 2 of C ...
Irshad M. Sulaiman+2 more
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An Improved Technique for Genotyping the ABCB1 Gene Variant of Exon 21
The Multidrug Resistance protein (ABCB1, MDR1) is involved in the transport of xenobiotics and antiretroviral drugs. Some variants of the ABCB1 gene are of clinical importance; among them, exon 12 (c.1236C>T, rs1128503), 21 (c.2677G>T/A, rs2032582), and 26 (c.3435C>T, rs1045642) have a high incidence in Caucasians.
Johanna Romina Zuccoli+5 more
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Evaluation of Cotton Genotypes Through the Selection Index Technique
Abstract Eight upland cotton genotypes introduced from different origins (BA440, FLASH, EDESSA, SPERO, IK259, W888, MONTANA and CANDIA) in addition to the two local cultivars (Coker 310 and Lachata) were cultivated on April 22 and 23, 2022 in the Rahmaniyah region at levels (0, 1, 2, and 3 g/liter). l) of nano-chelated NPK 20-20-20 under
Abdullah Moayad Omar+2 more
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Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]
Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
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