Results 1 to 10 of about 153,555 (331)

Graft-Derived Cell-Free DNA Quantification following Liver Transplantation Using Tissue-Specific DNA Methylation and Donor-Specific Genotyping Techniques: An Orthogonal Comparison Study [PDF]

open access: yesEpigenomes, 2023
Background: Graft-derived cell-free DNA (gdcfDNA) analysis has shown promise as a non-invasive tool for monitoring organ health following solid organ transplantation. A number of gdcfDNA analysis techniques have been described; however, the majority rely
Daniel R. A. Cox   +7 more
doaj   +2 more sources

An Overview of the Use of Genotyping Techniques for Assessing Genetic Diversity in Local Farm Animal Breeds [PDF]

open access: yesAnimals, 2021
Globally, many local farm animal breeds are threatened with extinction. However, these breeds contribute to the high amount of genetic diversity required to combat unforeseen future challenges of livestock production systems. To assess genetic diversity,
Anna Olschewsky, Dirk Hinrichs
doaj   +2 more sources

Recent Advances in Molecular Diagnosis of Pseudomonasaeruginosa Infection by State-of-the-Art Genotyping Techniques [PDF]

open access: yesFrontiers in Microbiology, 2018
Pseudomonas aeruginosa is a rod-shaped Gram-negative bacterium which is notably known as a pathogen in humans, animals, and plants. Infections caused by P.
Jian-Woon Chen   +6 more
doaj   +2 more sources

High resolution melt analysis (HRMA); a viable alternative to agarose gel electrophoresis for mouse genotyping. [PDF]

open access: yesPLoS ONE, 2012
Most mouse genetics laboratories maintain mouse strains that require genotyping in order to identify the genetically modified animals. The plethora of mutagenesis strategies and publicly available mouse alleles means that any one laboratory may maintain ...
Nicole Thomsen   +3 more
doaj   +2 more sources

A Novel Genome-Wide Association Study Approach Using Genotyping by Exome Sequencing Leads to the Identification of a Primary Open Angle Glaucoma Associated Inversion Disrupting ADAMTS17 [PDF]

open access: yes, 2015
Closed breeding populations in the dog in conjunction with advances in gene mapping and sequencing techniques facilitate mapping of autosomal recessive diseases and identification of novel disease-causing variants, often using unorthodox experimental ...
A McKenna   +27 more
core   +23 more sources

Development of an Assay to Distinguish Between Genotypes of the Leucyl-Cystinyl Aminopeptidase Gene

open access: yesRe:GEN Open, 2022
Introduction: The leucyl-cystinyl aminopeptidase gene rs4869317 single nucleotide polymorphism (SNP) is associated with multiple conditions; for example, patients with the rs4869317 TT genotype experiencing septic shock have increased plasma clearance ...
Nayan J. Sarma   +2 more
doaj   +1 more source

A new Trypanosoma cruzi genotyping method enables high resolution evolutionary analyses

open access: yesMemorias do Instituto Oswaldo Cruz, 2021
BACKGROUND Trypanosoma cruzi is an important human pathogen in Latin America with nearly seven million people infected. It has a large degree of genetic diversity, classified into six discrete typing units (DTUs), which probably influences its ...
Christian Macagnan Probst   +7 more
doaj   +1 more source

The Accuracy of Sequence-Specific Oligonucleotide and Real-Time Polymerase Chain Reaction HLA Typing in Determining the Presence of Pre-Transplant Donor-Specific Anti-HLA Antibodies and Total Eplet Mismatches for Deceased Donor Kidney Transplantation

open access: yesFrontiers in Immunology, 2022
High resolution human leukocyte antigen (HLA) typing is important in establishing eplet compatibility and the specificity of donor-specific anti-HLA antibodies (DSA).
Nicholas G. Larkins   +14 more
doaj   +1 more source

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