The genetics of cardiovascular disease [PDF]
Recent advances in genotyping technology and insights into disease mechanisms have increased interest in the genetics of cardiovascular disease. Several candidate genes involved in cardiovascular diseases were identified from studies using animal models,
Padmanabhan, S. +3 more
core +1 more source
Comparison of single nucleotide polymorphisms and microsatellites in non-invasive genetic monitoring of a wolf population [PDF]
Single nucleotide polymorphisms (SNPs) which represent the most widespread source of sequence variation in genomes, are becoming a routine application in several fields such as forensics, ecology and conservation genetics.
Fabbri Elena +7 more
doaj +1 more source
Genetic variability of blood groups in southern Brazil
We evaluated genetic variability among the blood groups Kell (c.578C > T and c.1790T > C), Kidd (c.838A > G), Duffy (c.125A > G, c.265C > T and c.1-67T > C), Diego (c.2561C > T), MNS (c.143T > C) and Rh (c.676G > C) in Rio Grande do Sul in southern ...
Gabriela Waskow +6 more
doaj +1 more source
Breed traceability of buffalo meat using microsatellite genotyping technique [PDF]
Although buffalo has emerged as a major meat producing animal in Asia, major research on breed traceability has so far been focused on cattle (beef). This research gap on buffalo breed traceability has impelled development and validation of buffalo breed traceability using a set of eight microsatellite (STR) markers in seven Indian buffalo breeds ...
Bheemashankar H, Kannur +4 more
openaire +2 more sources
Evaluation of a sticky trap for collecting Aedes (Stegomyia) adults in a dengue-endemic area in Thailand. [PDF]
Development of new operational techniques for collection and monitoring of adult Stegomyia mosquitoes is considered a pressing need for surveillance and prevention of arboviruses.
Valerio, Laura +15 more
core +1 more source
A new biosensor for noninvasive determination of fetal RHD status in maternal blood of RhD negative pregnant women. [PDF]
Prenatal detection of the fetal RHD status can be useful in the management of RhD incompatibility to identify fetuses at risk of hemolytic disease. Hemolytic disease causes morbidity and mortality of the fetus in the neonatal period.
Ebru Dündar Yenilmez +4 more
doaj +1 more source
The application of genotyping techniques to the epidemiological analysis ofCampylobacter jejuni [PDF]
SummaryCampylobacter jejuniserogroup reference strains and collections of sporadic and outbreak- associated isolates were examined for restriction fragment length polymorphisms (RFLPs), usingC. jejunirandom chromosomal and 16S rRNA gene probes. A collection of 48 Penner (HS) and 14 Lior (HL) serogroup reference strains, plus 10 clinical isolates ...
C J, Jackson +4 more
openaire +2 more sources
Statistical analysis of "Plasmodium falciparum" infection dynamics [PDF]
Malaria is one of the major contributors to the global burden of disease. Worldwide, there were an estimated number of 200 million malaria cases in the year 2008, with a vast majority (85%) of those being in the African Region.
Bretscher, Michael
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source

