Results 51 to 60 of about 83,652 (291)
Chinese Journal of Contemporary Neurology and Neurosurgery, 2020 Objective To explore the clinical efficacy of individualized therapy based on molecular classification in the treatment of medulloblastoma in children.
Wei SHI +5 more
doaj
Development of an Electrochemical Sensing Technique for Rapid Genotyping of Hepatitis B Virus [PDF]
Sensors, 2014 Objective: To develop a convenient; sensitive; accurate; and economical technique for genotyping of hepatitis B viruses (HBVs). Methods: The mercapto-modified B1; B2; C1; and C2-specific genotyping probes consisted of two probes for each HBV genotype that served as a double verification system. These probes were fixed on the surface of No. 1; 2; 3; and
Jinyuan Chen +8 more
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Crop Journal, 2023 Genomic selection (GS) is a powerful tool for improving genetic gain in maize breeding. However, its routine application in large-scale breeding pipelines is limited by the high cost of genotyping platforms.
Guangning Yu +12 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Individual Identification of Cartilage by Direct Amplification in Mass Disasters [PDF]
Fayixue Zazhi, 2017 Objective To explore the effectiveness of direct amplification for the STR analysis of cartilage, and to accelerate the effectiveness of disaster victim identification.
WANG CHUAN-HAI, XU CHENG, LI XIANG-QIN, ET AL.
doaj +1 more source
Evaluation of Cotton Genotypes Through the Selection Index Technique
IOP Conference Series: Earth and Environmental Science, 2023 Abstract Eight upland cotton genotypes introduced from different origins (BA440, FLASH, EDESSA, SPERO, IK259, W888, MONTANA and CANDIA) in addition to the two local cultivars (Coker 310 and Lachata) were cultivated on April 22 and 23, 2022 in the Rahmaniyah region at levels (0, 1, 2, and 3 g/liter). l) of nano-chelated NPK 20-20-20 under
Abdullah Moayad Omar +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
PLoS ONE, 2017 An analysis of the population structure and genetic diversity for any organism often depends on one or more molecular marker techniques. Nonetheless, these techniques are not absolutely reliable because of various sources of errors arising during the ...
Jakub Vašek +5 more
doaj +1 more source