Results 71 to 80 of about 5,436,069 (302)

Genotyping of dermatophyte fungal species by AP-PCR technique

International journal of health sciences, 2022
Dermatophytes fungi are causative agents of dermatophytosis. Surface skin fungi are called dermatophytes after the anatomical localization of the lesions. A total of 164 specimens were collected from patients with dermatophytosis (ring worm) distributed into 89/164(54.26%) specimens from male and 75/164(45.73%) specimens from female.
Ali Meteab Khalaf, Raed Ali Hussain Shabaa   +1 more
openaire   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Genotyping Techniques for Determining the Diversity of Microorganisms

, 2012
Typing of microbial pathogens, or identifying bacteria at the strain level, is particularly important for diagnosis, treatment, and epidemiological surveillance of bacterial infections. This is especially the case for bacteria exhibiting high levels of antibiotic resistance or virulence, and those involved in nosocomial or pandemic infections.
Katarzyna Wolska, Piotr Szwe
openaire   +2 more sources

A novel technique for NOD2/CARD15 genotyping using PCR-SSP

Journal of Immunological Methods, 2007
The Nucleotide-binding Oligomerisation Domain (NOD) 2 protein is encoded by the Caspase Recruitment Domain (CARD) 15 gene and has a critical role in innate immunity. Recent studies have implicated Single Nucleotide Polymorphisms (SNPs) of the NOD2/CARD15 gene with the onset of several Inflammatory Bowel Disorders (Crohn's Disease, Blau syndrome) and ...
Mayor, N, Shaw, B, Keshav, S, Madrigal, J, Marsh, S   +4 more
openaire   +3 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

The Identification of Pompe Disease Mutations in Archival Tissues and Development of a Rapid Molecular-based Test

Sultan Qaboos University Medical Journal, 2013
Objectives: Pompe disease (glycogen storage disease type II) is a rare autosomal recessive lysosomal storage disease that is caused by acid alpha-glucosidase deficiency.
Aliya Alansari, Samira Al-Rawahi, Taher Ba-Omar, Mariam Al-Nabhani, Anand Date   +4 more
doaj  

GENOTYPING OF THE HUMAN IMMUNODEFICIENCY VIRUS AND PATTERNS OF RESISTANCE TO ANTIRETROVIRALS IN SOUTHERN SANTA CATARINA

Brazilian Journal of Infectious Diseases
Introduction/Objectives: The Human Immunodeficiency Virus (HIV), which can cause AIDS, remains a major global public health issue. Therapeutic advances have succeeded in increasing survival and improving the quality of life of patients living with the ...
Chaiana Esmeraldino Mendes Marcon, Allyson Maciel Candido, Laís Villa Demétrio, Danilo Assunção, Alessandra Machado Cordella, Aline Daiane Schlindwein, Fabiana Schuelter Trevisol   +6 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

vgteam/sv-genotyping-paper: Revised code repository for "Genotyping structural variants in pangenome graphs using the vg toolkit"

, 2019
This repository contains the commands and scripts used for the revised version of our manuscript Genotyping structural variants in pangenome graphs using the vg toolkit ...
Glenn Hickey, Jean Monlong, David Heller
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source