Results 61 to 70 of about 5,436,069 (302)

Six novel O genotypes from Shiga toxin-producing Escherichia coli

Frontiers in Microbiology, 2016
Serotyping is one of the typing techniques used to classify strains within the same species. O-serogroup diversification shows a strong association with the genetic diversity of O-antigen biosynthesis genes.
Atsushi eIguchi, Sunao eIyoda, Kazuko eSeto, Hironobu eNishii, Makoto eOhnishi, Hirohisa eMekata, Hirohisa eMekata, Yoshitoshi eOgura, Tetsuya eHayashi   +8 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

RHD genotyping by allele specific “Loop-mediated isothermal DNA Amplification”

Bioingeniøren, 2014
Background: The “Rh” cluster, with its main antigen D, is the most important blood group system after “ABO”. Because anti-D antibodies can cause hemolytic disease of the fetus and newborn as well as hemolytic transfusion reactions, phenotyping for RhD is
Thomas Hundhausen, Nancy Lacsamana, Uraiwan Tedenes, Audun Slettan   +3 more
doaj  

Phenotypic and genotypic evaluation of slime production by conventional and molecular microbiological techniques

Microbiological Research, 2009
Twenty-nine staphylococcal isolates from different clinical samples were tested for slime production: phenotypic characterization was carried out using Christensen test (tube test) and Congo red agar plate test (CRA plate test), while the presence and expression of icaA and icaD genes were evaluated by real-time PCR.
LIBERTO MC, MATERA G, QUIRINO A, LAMBERTI AG, CAPICOTTO R, PUCCIO R, BARRECA, GS, FOCA E, CASCIO A., FOCA A   +10 more
openaire   +3 more sources

Genotyping streptococcus pneumoniae [PDF]

, 2015
Streptococcus pneumoniae is a potentially deadly human pathogen associated with high morbidity, mortality and global economic burden. The universally used bacterial\ud genotyping methods are multilocus sequence typing and pulsed field gel electrophoresis.
Savill, John, Huygens, Flavia, Rayner, Rachael, Hafner, Louise M.   +3 more
core   +1 more source

Palmer Lab Heterogeneous Stock Rats Genotyping Pipeline

, 2023
<p>The third version of Palmer Lab's HS Rats Genotyping Pipeline v3.0.0. Acceptable sequencing data: Riptide library prep lc-WGS, and ddGBS sequences Genotype calling and imputation: STITCH niteration=2 with a high quality consensus reference ...
Chitre, Apurva, Cheng, Riyan, Palmer, Abraham, Polesskaya, Oksana, Chen, Denghui, Peng, Beverly   +5 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Genomic Characterization of the Vaccinal Strain of Mycobacterium Avium Subspecies Paratuberculosis (MAP) 316F by MIRU-VNTR

Medical Laboratory Journal, 2015
Background and Objective: Paratuberculosis is a chronic granulomatous enteritis of ruminants caused by Mycobacterium avium subspecies paratuberculosis (MAP). this study aimed to characterize the genome of the MAP 316F strain.
Zahra Ebrahim, Keyvan Tadayon, Nader Mosavari   +2 more
doaj  

GAWMerge expands GWAS sample size and diversity by combining array-based genotyping and whole-genome sequencing

Communications Biology, 2022
GAWMerge is a computational tool that allows users to integrate SNP genotyping data from array techniques or whole-genome sequencing, providing a feasible method to leverage existing cohorts to increase sample size in genetic studies.
Ravi Mathur, Fang Fang, Nathan Gaddis, Dana B. Hancock, Michael H. Cho, John E. Hokanson, Laura J. Bierut, Sharon M. Lutz, Kendra Young, Albert V. Smith, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Edwin K. Silverman, Grier P. Page, Eric O. Johnson   +13 more
doaj   +1 more source

A novel technique for rapid automated genotyping of DNA polymorphisms in the mouse

Molecular and Cellular Probes, 1999
The ability to rapidly and reliably genotype mice is an important concern. Traditional methods employ labour intensive and time consuming techniques such as test crossing, gel electrophoresis or nucleic acid hybridization. Here we show that a new molecular biology workstation, the WAVE DNA Fragment Analysis System, can easily resolve polymerase chain ...
A, Kuklin, A P, Davis, K H, Hecker, D T, Gjerde, P D, Taylor   +4 more
openaire   +2 more sources