Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT [PDF]
, 2020 Background The development of prostate cancer can be influenced by genetic and environmental factors. Numerous germline SNPs influence prostate cancer susceptibility.
Ahmed, M +7 more
core +2 more sources
Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]
, 2011 Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
core +1 more source
Advance in Genomics of Rare Genetic Diseases
Biomolecules, 2023 Recent technical breakthroughs in genotyping and bioinformatics techniques have greatly facilitated the translation of genomics into clinical care [...]
Elena Sommariva +2 more
doaj +1 more source
High Levels of CXCL8 and Low Levels of CXCL9 and CXCL10 in Women with Maternal RhD Alloimmunization
Frontiers in Immunology, 2017 Maternal RhD alloimmunization is an inflammatory response against protein antigens in fetal red blood cells (RBC). However, not all women become alloimmunized when exposed to RhD+ fetal RBC.
Juliana Araújo de Carvalho Schettini +8 more
doaj +1 more source
A comparison of BeadChip and WGS genotyping outputs using partial validation by sanger sequencing
BMC Genomics, 2020 Background Head-to-head comparison of BeadChip and WGS/WES genotyping techniques for their precision is far from straightforward. A tool for validation of high-throughput genotyping calls such as Sanger sequencing is neither scalable nor practical for ...
Kirill A. Danilov +3 more
doaj +1 more source
Breed traceability of buffalo meat using microsatellite genotyping technique [PDF]
Journal of Food Science and Technology, 2017 Although buffalo has emerged as a major meat producing animal in Asia, major research on breed traceability has so far been focused on cattle (beef). This research gap on buffalo breed traceability has impelled development and validation of buffalo breed traceability using a set of eight microsatellite (STR) markers in seven Indian buffalo breeds ...
Bheemashankar H, Kannur +4 more
openaire +2 more sources
High-resolution genotyping via whole genome hybridizations to microarrays containing long oligonucleotide probes. [PDF]
PLoS ONE, 2010 To date, microarray-based genotyping of large, complex plant genomes has been complicated by the need to perform genome complexity reduction to obtain sufficiently strong hybridization signals. Genome complexity reduction techniques are, however, tedious
Yan Fu +10 more
doaj +1 more source
Validation of a Polymerase Chain Reaction technique for Kidd blood group genotyping [PDF]
, 2015 The Kidd blood group antigens, Jkª and Jkᵇ , are two of the main surface markers which are found on the membrane of red blood cells. The determination of whether a donor or a recipient has the Jkª and/or the Jkᵇ antigens is crucially important to ...
Borg, Joseph J. +2 more
core +1 more source
Genotyping Techniques to Address Diversity in Tumors [PDF]
, 2011 Array-based genotyping platforms have during recent years been established as a valuable tool for the characterization of genomic alterations in cancer. The analysis of tumor samples, however, presents challenges for data analysis and interpretation.
Lindgren, David +2 more
openaire +4 more sources
2b-RAD genotyping for population genomic studies of Chagas disease vectors: Rhodnius ecuadoriensis in Ecuador [PDF]
, 2017 Background: Rhodnius ecuadoriensis is the main triatomine vector of Chagas disease, American trypanosomiasis, in Southern Ecuador and Northern Peru.
Andersson, Björn +10 more
core +4 more sources