Results 71 to 80 of about 3,588 (226)
Abstract Purpose The presence of a sinus tract in chronic periprosthetic joint infection (PJI) has traditionally been considered a contraindication to single‐stage total knee arthroplasty (TKA) revision. However, an increasing number of surgeons are now performing single‐stage revisions in this context, despite limited comparative data.
Arthur Barbaret +12 more
wiley +1 more source
Ménière's Disease: A Tri‐Decade Scoping Review of Treatment Trends and Evidence Quality
This tri‐decade scoping review of Ménière's disease literature reveals a significant increase in high‐level evidence and a clinical pivot toward hearing‐preserving interventions, such as intratympanic steroids and cochlear implants. However, a significant quality paradox has emerged, where adherence to standardized AAO‐HNS reporting and diagnostic ...
Ofir Zavdy +4 more
wiley +1 more source
Abstract Biological nitrogen fixation in symbiotic diazotrophs is subject to oxygen regulation by an oxygen‐sensing FixLJ two‐component system under micro‐oxic conditions. However, it remains unclear whether this mechanism is conserved in free‐living diazotrophs.
Lingwei Cui +6 more
wiley +1 more source
We developed a genome‐integrated CRISPR/Cas12a system for Xenorhabdus budapestensis XBD8, which enables precise deletion or replacement of DNA fragments ranging from 379 to 45,168 bp, with a success rate exceeding 90%. Application of this tool for the dynamic regulation of fabclavine‐8 biosynthesis resulted in a 1.90‐fold increase in production ...
Wenfeng Gan +4 more
wiley +1 more source
Genetic underpinnings of type-2 diabetes (T2D) with colorectal cancer (CRC): In-silico discovery of common molecular signatures, pathogenetic processes and therapeutic candidates. [PDF]
Ahmmed R +7 more
europepmc +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
Screening biomarkers related to cholesterol metabolism in osteoarthritis based on transcriptomics. [PDF]
Lao C +7 more
europepmc +1 more source
Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren +7 more
wiley +1 more source
Cystatin C for gentamicin dosing - a case study. [PDF]
Šálek T +3 more
europepmc +1 more source
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen +7 more
wiley +1 more source

