Results 81 to 90 of about 3,783 (266)
KINETIC SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF GENTAMICIN IN PHARMACEUTICAL FORMS [PDF]
, 2015 Objective: The objective of this study is to develop and validate new selective kinetic methods for the determination of Gentamicin in pure and pharmaceutical preparations.Methods: The proposed methods (A and B) are based on the oxidation of Gentamicin ...
Fraihat, Safwan
core
ANALYTICAL METHODS FOR THE DETERMINATION OF AMINOGLYCOSIDES ANTIBIOTICS BY CHROMATROGRAPHIC TECHNIQUE [PDF]
, 2020 Aminoglycosides antibiotics are considered to be the antimicrobial agents used frequently in the treatment of human diseases caused by a bacterial infection.
KUMARI, PREMA +2 more
core +1 more source
Advances in the analysis of veterinary drug residues in food matrices by capillary electrophoresis techniques [PDF]
, 2019 In the last years, the European Commission has adopted restrictive directives on food quality and safety in order to protect animal and human health.
Colombo Raffaella, Papetti Adele
core +1 more source
Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes
Biotechnology and Bioengineering, EarlyView.ABSTRACT Bioelectronic systems that enable seamless communication between electronic devices and living systems represent a transformative frontier in biotechnology. Among available methodologies, redox based signaling offers unique advantages due to its ubiquity in biology and compatibility with standard electrochemical equipment, expanding on ...
Eric VanArsdale +8 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT The detergent Triton X‐100 (TX‐100) is a typical component of solvent/detergent (S/D) mixes applied for virus inactivation steps of biomanufacturing processes, yet environmentally unfavorable properties have led to restrictions on its use. Deviron 13‐S9 has recently been described as an eco‐friendly TX‐100 alternative, with powerful virus ...
Johanna Kindermann +3 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Using kanamycin A as a model target, we developed click‐capture SELEX to identify nucleobase‐modified aptamers capable of binding small molecules in solution. This approach enables flexible incorporation of nucleobase modifications via CuAAC, allowing the chemical properties of the aptamer to be tailored to the target molecule.
Philipp Menke +5 more
wiley +1 more source
Aminoglycoside resistance in clinical Gram-negative isolates from Norway [PDF]
, 2011 Aminoglycosides represent an important class of antimicrobial agents. The prevalence of aminoglycoside resistance among Gram-negative bacteria in Norway is low, but an increased prevalence among clinical isolates of Escherichia coli has been observed ...
Haldorsen, Bjørg Christina
core
Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1
Cytoskeleton, EarlyView.ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley +1 more source
Molecular determinants of ligand specificity of aminoglycoside acetyltransferases [PDF]
, 2018 Bacteria can acquire resistance against antibiotics by covalently modifying them. This is achieved by plasmid-encoded enzymes called as aminoglycoside modifying enzymes (AGMEs).
Prashasti, FNU
core +1 more source