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Gentiana macrophylla flavonoids from Tibetan medicine decreases circ_0059665 to alleviate the progression of non‐small cell lung cancer under hypoxia [PDF]

open access: yesThoracic Cancer
Background Gentiana macrophylla Pall. is a traditional Tibetan medicinal herb possessing antinociceptive and anti‐inflammatory activities. Circular RNAs (circRNAs) have been identified to be involved in the tumorigenesis of non‐small cell lung cancer ...
Guilin Jin
exaly   +3 more sources

Terpenoid Glucosides from Gentiana macrophylla That Attenuate TNF-α Induced Pulmonary Inflammation in A549 Cells [PDF]

open access: yesMolecules, 2023
Four previously undescribed terpenoid glucosides, including one sesquiterpenoid di-glucoside (1), two new iridoid glucosides (2, 3), and a new triterpenoid tri-glucoside (4), were isolated from a 70% ethanol extract of the root of Gentiana macrophylla ...
Pei-Qi Huang   +9 more
doaj   +2 more sources

The complete chloroplast genome of Gentiana macrophylla [PDF]

open access: yesMitochondrial DNA. Part B. Resources, 2017
Gentiana macrophylla is a perennial medicinal plant in the family Gentianaceae. Natural sources for G. macrophylla plants are being exhausted due to over-collection and need urgent conservation. The complete chloroplast DNA sequence of G.
Xiaofan Wang   +4 more
doaj   +2 more sources

Transcriptional Responses and Gentiopicroside Biosynthesis in Methyl Jasmonate-Treated Gentiana macrophylla Seedlings. [PDF]

open access: yesPLoS ONE, 2016
Gentiana macrophylla, a medicinal plant with significant pharmacological properties, contains the bioactive compound gentiopicroside. Methyl jasmonate (MeJA) is an effective elicitor for enhancing the production of such compounds.
Xiaoyan Cao   +7 more
doaj   +2 more sources

Integrative Transcriptome and Metabolome Analysis Reveals the Regulatory Networks and Key Biosynthetic Pathway Genes of Wild and Cultivated Gentiana macrophylla Pall [PDF]

open access: yesMetabolites
Objectives: Gentiana macrophylla Pall. (Gentianaceae) is a medicinally important perennial herb. Iridoids are the main chemical constituents of G. macrophylla. The scarcity of the wild resource has led to increased attention to cultivated G. macrophylla.
Juanjuan Liu   +6 more
doaj   +2 more sources

Genomic characterization of WRKY transcription factors related to secoiridoid biosynthesis in Gentiana macrophylla [PDF]

open access: yesBMC Plant Biology
Gentiana macrophylla is one of Chinese herbal medicines in which 4 kinds of iridoids or secoiridoids, such as loganic acid, sweroside, swertiamarin, and gentiopicroside, are identified as the dominant medicinal secondary metabolites.
Yangyang Yin   +7 more
doaj   +2 more sources

The Root Extract of Gentiana macrophylla Pall. Alleviates Cardiac Apoptosis in Lupus Prone Mice. [PDF]

open access: yesPLoS ONE, 2015
The roots of the perennial herb Gentiana macrophylla Pall. (GM) are known as Qinjiao, which has been used for centuries to treat systemic lupus erythematosus (SLE).
Chih-Yang Huang   +7 more
doaj   +2 more sources

Pathogen identification of Gentiana macrophylla root-knot nematode disease in Yulong, China [PDF]

open access: yesJournal of Nematology, 2021
Wentao Wu   +6 more
doaj   +2 more sources

The Hepatoprotective Properties of Gentiopicroside, Sweroside, and Swertiamarin Against Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) [PDF]

open access: yesBiomolecules
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a metabolic disease characterised by the accumulation of fat in the liver. It is estimated that 30–38% of the world’s adult population have MASLD, making it the most prevalent global ...
Anthony O. Boateng   +2 more
doaj   +2 more sources

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