Results 11 to 20 of about 215 (114)

ChnagG Plays the Role of 5-Salicylate Hydroxylase in the Gentisic Acid Pathway of Salicylic Acid Metabolism in Cochliobolus heterostrophus. [PDF]

open access: yesMol Plant Pathol
The ChnagG gene in Cochliobolus heterostrophus encodes 5‐salicylate hydroxylase, converting salicylic acid (SA) to gentisic acid, enhancing pathogenicity and suppressing plant SA signalling‐mediated defences during infection. ABSTRACT Salicylic acid (SA) plays a crucial role in the defence strategies of plants against fungal pathogens.
Xu Y   +6 more
europepmc   +2 more sources

Bringing up to date the toolkit for the catabolism of aromatic compounds in fungi: The unexpected 1,2,3,5-tetrahydroxybenzene central pathway. [PDF]

open access: yesMicrob Biotechnol
Our understanding of how fungi utilize gallate or other syringyl derivatives is, to date, scarce and mostly relies on unproven assumptions. This study demonstrates the existence of a new 1,2,3,5‐tetrahydroxybenzene central pathway for the catabolism of gallate and related compounds in numerous fungi.
Martins TM   +5 more
europepmc   +2 more sources

Expanding Antarctic biogeography: microbial ecology of Antarctic island soils

open access: yesEcography, Volume 2023, Issue 9, September 2023., 2023
The majority of islands surrounding the Antarctic continent are poorly characterized in terms of microbial macroecology due to their remote locations, geographical isolation and access difficulties. The 2016/2017 Antarctic Circumnavigation Expedition (ACE) provided unprecedented access to a number of these islands.
Pedro H. Lebre   +14 more
wiley   +1 more source

Crystal structure of the monocupin ring‐cleaving dioxygenase 5‐nitrosalicylate 1,2‐dioxygenase from Bradyrhizobium sp.

open access: yesActa Crystallographica Section D, Volume 79, Issue 7, Page 632-640, July 2023., 2023
The crystal structure of the monocupin 5‐nitrosalicylate 1,2‐dioxygenase, an iron(II)‐dependent ring‐cleaving dioxygenase, from Bradyrhizobium sp. was determined by molecular replacement using a theoretical model obtained by AlphaFold2. Comparison with structures of other members of the same class and docking of the substrate allowed identification of ...
Erik Eppinger   +2 more
wiley   +1 more source

Emerging roles for thiol dioxygenases as oxygen sensors

open access: yesThe FEBS Journal, Volume 289, Issue 18, Page 5426-5439, September 2022., 2022
Thiol dioxygenases (TDOs) catalyse oxidation of thiols to sulphinates. Recent reports identify TDOs which catalyse oxidation of N‐terminal cysteine residues of protein substrates in an O2‐sensitive manner, promoting degradation: N‐terminal cysteinyl dioxygenases (NCOs). These appear to form a separate subclass of TDO from those which catalyse oxidation
Dona M. Gunawardana   +2 more
wiley   +1 more source

A structurally unique Fusobacterium nucleatum tannase provides detoxicant activity against gallotannins and pathogen resistance

open access: yesMicrobial Biotechnology, Volume 15, Issue 2, Page 648-667, February 2022., 2022
A new tannase enzyme from the cancer‐related pathogen Fusobacterium nucleatum is important for the survival of the bacteria under the stress conditions derived from the presence of dietary gallotannins. Using structural studies and molecular modelling we describe new structural features for this enzyme.
José Miguel Mancheño   +23 more
wiley   +1 more source

The ß‐ketoadipate pathway of Acinetobacter baumannii is involved in complement resistance and affects resistance against aromatic antibiotics

open access: yesEnvironmental Microbiology Reports, Volume 14, Issue 1, Page 170-178, February 2022., 2022
Summary Acinetobacter baumannii can thrive on a broad range of substrates such as sugars, alcohols, lipids, amino acids and aromatic compounds. The latter three are abundant in the human host and are potential candidates as carbon sources for the metabolic adaptation of A. baumannii to the human host.
Jennifer Breisch   +4 more
wiley   +1 more source

PahT regulates carbon fluxes in Novosphingobium sp. HR1a and influences its survival in soil and rhizospheres

open access: yesEnvironmental Microbiology, Volume 23, Issue 6, Page 2969-2991, June 2021., 2021
Summary Novosphingobium sp. HR1a is a good biodegrader of PAHs and aromatic compounds, and also a good colonizer of rhizospheric environments. It was previously demonstrated that this microbe is able to co‐metabolize nutrients existing in root exudates together with the PAHs.
Ana Segura   +2 more
wiley   +1 more source

Peganum spp.: A Comprehensive Review on Bioactivities and Health‐Enhancing Effects and Their Potential for the Formulation of Functional Foods and Pharmaceutical Drugs

open access: yesOxidative Medicine and Cellular Longevity, Volume 2021, Issue 1, 2021., 2021
The genus Peganum includes four species widely distributed in warm temperate to subtropical regions from the Mediterranean to Mongolia as well as certain regions in America. Among these species, Peganum harmala L., distributed from the Mediterranean region to Central Asia, has been studied and its phytochemical profile, traditional folk use, and ...
Javad Sharifi-Rad   +21 more
wiley   +1 more source

Flavoenzyme‐mediated Regioselective Aromatic Hydroxylation with Coenzyme Biomimetics

open access: yesChemCatChem, Volume 12, Issue 5, Page 1368-1375, March 6, 2020., 2020
Kiss and ride: Biomimetic coenzymes can promote catalysis with flavin‐containing hydroxylase enzymes for the regioselective oxidation of aromatic compounds, without producing H2O2. Abstract Regioselective aromatic hydroxylation is desirable for the production of valuable compounds.
Alice Guarneri   +8 more
wiley   +1 more source

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