Results 31 to 40 of about 19,202 (230)
Test–retest variability of microperimetry in geographic atrophy
International Journal of Retina and Vitreous, 2020 Purpose Microperimetry (MP) allows for measurement of retinal sensitivity at precise locations and is now commonly employed as a clinical trial endpoint.
A. Yasin Alibhai +7 more
doaj +1 more source
Treating patients with geographic atrophy: are we there yet?
International Journal of Retina and Vitreous, 2023 Geographic atrophy (GA) is a progressive degenerative disease that significantly contributes to visual impairment in individuals aged 50 years and older. The development of GA is influenced by various modifiable and non-modifiable risk factors, including
Bani Antonio-Aguirre +1 more
doaj +1 more source
Methodological Appraisal of Phase 3 Clinical Trials in Geographic Atrophy
Biomedicines, 2023 Geographic atrophy (GA) secondary to age-related macular degeneration is a common cause of blindness worldwide. Given the recent approval of the first therapy for GA, pegcetacoplan, we critically appraise methodological aspects of the phase 3 clinical ...
Marc Biarnés +8 more
doaj +1 more source
Choriocapillaris Degeneration in Geographic Atrophy [PDF]
The American Journal of Pathology, 2019 Early age-related macular degeneration (AMD) is characterized by degeneration of the choriocapillaris, the vascular supply of retinal photoreceptor cells. We assessed vascular loss during disease progression in the choriocapillaris and larger vessels in the deeper choroid.
Elliott H. Sohn +11 more
openaire +2 more sources
Living with Geographic Atrophy: An Ethnographic Study
Ophthalmology and Therapy, 2019 Introduction The specific impact from the patient’s perspective of geographic atrophy (GA), an advanced form of age-related macular degeneration (AMD), is not well understood.
Sobha Sivaprasad +7 more
doaj +1 more source
Indian Journal of Ophthalmology, 2015 Purpose: To provide a detailed analysis of age-related macular degeneration (AMD) with a 5-year follow-up at a Tertiary Eye Care Center in India. Methods: In this retrospective institutional study, 408 eyes of 204 subjects (100 males) with a diagnosis of
Aditya Sudhalkar +5 more
doaj +1 more source
MMP-2 Rs24386 (C-->T) gene polymorphism and the phenotype of age-related macular degeneration [PDF]
International Journal of Ophthalmology, 2017 AIM: To examine the MMP-2 (-1306 C/T) gene polymorphism and the phenotype characterized by soft and hard drusen of early age-related macular degeneration (AMD) and geographic atrophy of late AMD form.
Rasa Liutkeviciene +6 more
doaj +1 more source
Association of Anti-VEGF Injections with Progression of Geographic Atrophy
Ophthalmology and Eye Diseases, 2016 Age-related macular degeneration (AMD) is one of the leading causes of blindness in developed countries in people over the age of 60 years. One of the forms of advanced AMD is wet AMD.
Ryan Enslow +5 more
doaj +2 more sources
Scientific Reports, 2023 To compare clinical and imaging characteristics of extensive macular atrophy with pseudodrusen-like appearance (EMAP) versus diffuse-trickling geographic atrophy (DTGA) and non-diffuse-trickling geographic atrophy (nDTGA) phenotypes of age-related ...
Alessio Antropoli +7 more
doaj +1 more source
Geographic Atrophy after Reabsorption of Pigment Epithelial Detachment (GARPED) study
BMC Ophthalmology, 2023 Background To describe the occurrence, rate of geographic atrophy (GA) expansion, and changes in visual acuity (VA) after reabsorption of subfoveal pigment epithelial detachments (PED).
Enoch T. Peng, Sean D. Adrean
doaj +1 more source