Results 31 to 40 of about 1,535,618 (326)

Optical Coherence Tomographic Angiography Imaging in Age-Related Macular Degeneration. [PDF]

, 2017
Optical coherence tomographic angiography (OCTA) is emerging as a rapid, noninvasive imaging modality that can provide detailed structural and flow information on retinal and choroidal vasculature.
Desai, Ria, Fawzi, Amani, Gill, Manjot, Ma, Jeffrey, Nesper, Peter, Skondra, Dimitra   +5 more
core   +3 more sources

Clinicopathologic Findings in Three Siblings With Geographic Atrophy

Investigative Ophthalmology and Visual Science, 2023
Purpose Age-related macular degeneration (AMD) is a leading cause of blindness among the elderly worldwide. Clinical imaging and histopathologic studies are crucial to understanding disease pathology.
M. Edwards, D. Mcleod, Mengxi Shen, R. Grebe, J. Sunness, I. Bhutto, Erin McDonnell, Alexandra Pado, Giovanni Gregori, P. Rosenfeld, G. Lutty   +10 more
semanticscholar   +1 more source

Vascular Response to Sildenafil Citrate in Aging and Age-Related Macular Degeneration. [PDF]

, 2019
Age-related macular degeneration (AMD) - the leading cause of vision loss in the elderly - share many risks factors as atherosclerosis, which exhibits loss of vascular compliance resulting from aging and oxidative stress.
Agrawal, Rupesh, Cheung, Chui Ming Gemmy, Cunefare, David, Farsiu, Sina, Khandelwal, Neha, Migacz, Justin, Tran, Steven, Vuong, Vivian S, Yiu, Glenn   +8 more
core   +2 more sources

Geographic Atrophy Segmentation Using Multimodal Deep Learning

Translational Vision Science & Technology, 2023
Purpose To examine deep learning (DL)–based methods for accurate segmentation of geographic atrophy (GA) lesions using fundus autofluorescence (FAF) and near-infrared (NIR) images. Methods This retrospective analysis utilized imaging data from study eyes
Ted Spaide, Jiaxiang Jiang, Jasmine Patil, Neha Anegondi, Verena Steffen, M. Kawczynski, Elizabeth M. Newton, C. Rabe, Simon S. Gao, Aaron Y. Lee, F. Holz, S. Sadda, S. Schmitz-Valckenberg, Daniela Ferrara   +13 more
semanticscholar   +1 more source

Ataxia with oculomotor apraxia type 2: clinical, biological and genotype/phenotype correlation study of a cohort of 90 patients [PDF]

, 2009
Ataxia with oculomotor apraxia type 2 (AOA2) is an autosomal recessive disease due to mutations in the senataxin gene, causing progressive cerebellar ataxia with peripheral neuropathy, cerebellar atrophy, occasional oculomotor apraxia and elevated alpha ...
Ali-Pacha, L, Anheim, M, Arning, L, Barbot, C, Benhassine, T, Brice, A, Chabrol, B, Charles, P, Chbicheb, M, Coutinho, P, De Bleecker, Jan, Delaunoy, JP, Drouot, N, Durr, A, Fleury, M, Fritsch, M, Gazulla, J, Goizet, C, Hamri, A, Koenig, M, Koht, J, Le Ber, I, M'Zahem, A, Marelli, C, Monga, B, Mukhtar, M, Murphy, R, Pouget, J, Salih, M, Schols, L, Sequeiros, J, Synofzik, M, Tazir, M, Tranchant, C, Watanabe, M   +34 more
core   +1 more source

Advancements in the treatment of geographic atrophy: focus on pegcetacoplan in age-related macular degeneration

Annals of Medicine and Surgery, 2023
Geographic atrophy (GA) is a progressive form of age-related macular degeneration characterized by the degeneration of retinal pigment epithelial cells and photoreceptor death.
Abdullah Nadeem, Inshal Arshad Malik, Fariha Shariq, E. K. Afridi, Muhammad Taha, Nahid Raufi, A. Naveed, Javed Iqbal, Alexander Habte   +8 more
semanticscholar   +1 more source

Living with Geographic Atrophy: An Ethnographic Study

Ophthalmology and Therapy, 2019
Introduction The specific impact from the patient’s perspective of geographic atrophy (GA), an advanced form of age-related macular degeneration (AMD), is not well understood.
Sobha Sivaprasad, Elizabeth A. Tschosik, Robyn H. Guymer, Audrey Kapre, Ivan J. Suñer, Antonia M. Joussen, Paolo Lanzetta, Daniela Ferrara   +7 more
doaj   +1 more source

Vision-related quality of life is selectively affected by comorbidities in patients with geographic atrophy

BMC Ophthalmology, 2023
Background The atrophic late stage of age-related macular degeneration (AMD) is termed geographic atrophy (GA), and affects visual acuity (VA) as well as quality of life (QoL).
Ditte-Marie Leegaard Holm, M. K. Nielsen, Birte Bay Højsted, T. Sørensen   +3 more
semanticscholar   +1 more source

Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]

, 2017
Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson, Giacomo Panozzo, Giorgio Boschi, Giuseppe Scarpa, Nicola Zemella, null null, Sandro Saviano, Stefania Miotto, Stefano Piermarocchi   +8 more
core   +1 more source

MMP-2 Rs24386 (C-->T) gene polymorphism and the phenotype of age-related macular degeneration [PDF]

International Journal of Ophthalmology, 2017
AIM: To examine the MMP-2 (-1306 C/T) gene polymorphism and the phenotype characterized by soft and hard drusen of early age-related macular degeneration (AMD) and geographic atrophy of late AMD form.
Rasa Liutkeviciene, Vaiva Lesauskaite, Giedre Sinkunaite-Marsalkiene, Sandrita Simonyte, Reda Zemaitiene, Loresa Kriauciuniene, Dalia Zaliuniene   +6 more
doaj   +1 more source