Results 41 to 50 of about 4,553,166 (289)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Optimal power mean bounds for the second Yang mean

open access: yesJournal of Inequalities and Applications, 2016
In this paper, we present the best possible parameters p and q such that the double inequality M p ( a , b ) < V ( a , b ) < M q ( a , b ) $$ M_{p}(a,b)< V(a,b)< M_{q}(a,b) $$ holds for all a , b > 0 $a, b>0$ with a ≠ b $a\neq b$ , where M r ( a , b ) = [
Jun-Feng Li, Zhen-Hang Yang, Yu-Ming Chu
doaj   +1 more source

Land Suitability of Urban and Industrial Development Using Multi-Criteria Evaluation (MCE) and A New Model by GIS in Fasa County, Iran

open access: yesLand, 2023
Land use planning is a science that specifies the optimized use of land based on ecological and socioeconomic characteristics. In many parts of Iran, the selection and management of land use (development, especially) is performed regardless of land ...
Masoud Masoudi   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The geometric mean concentrations of anti-pneumococcal IgG antibodies (μg/ mL, 95% confidence intervals of the geometric mean).

open access: yes, 2022
The geometric mean concentrations of anti-pneumococcal IgG antibodies (μg/ mL, 95% confidence intervals of the geometric mean).
Eli B. Nix (12418705)   +5 more
core   +1 more source

Bias Reduction in Robust Mean–Geometric Mean Linking via SIMEX

open access: yesAlgorithms
Robust mean–geometric mean (MGM) linking is a method for comparing the performance of two groups on a test involving dichotomous items and is particularly suited to settings with fixed and sparse differential item functioning (DIF).
Alexander Robitzsch
doaj   +1 more source

Spatial and temporal zoning of watershed resilience using a multidimensional composition approach

open access: yesNatural Resource Modeling, 2023
The present initiative study has been planned to develop a conceptual model for watershed resilience for which rare documents have been reported yet, particularly in developing countries where such studies are necessary.
Parisa Farzi   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

New weighted geometric mean method to estimate the slope of measurement error model [PDF]

open access: yes, 2014
This paper introduces a new weighted geometric mean (WG) estimator to fit regression line when both the response and explanatory variables are subject to measurement errors.
Saqr, Anwar, Khan, Shahjahan
core  

Geometric mean and standard geometric deviation of groups.

open access: yes, 2014
Data are presented as geometric mean (GM) and geometric standard deviation (GSD).Geometric mean and standard geometric deviation of groups.
Flávia Valladão Thiesen (680124)   +4 more
core   +1 more source

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