Results 51 to 60 of about 4,312,747 (279)

Optimal power mean bounds for the second Yang mean

open access: yesJournal of Inequalities and Applications, 2016
In this paper, we present the best possible parameters p and q such that the double inequality M p ( a , b ) < V ( a , b ) < M q ( a , b ) $$ M_{p}(a,b)< V(a,b)< M_{q}(a,b) $$ holds for all a , b > 0 $a, b>0$ with a ≠ b $a\neq b$ , where M r ( a , b ) = [
Jun-Feng Li, Zhen-Hang Yang, Yu-Ming Chu
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Geometric means provide a biased efficacy result when conducting a faecal egg count reduction test (FECRT) [PDF]

open access: yes, 2009
The process of conducting a faecal egg count reduction test was simulated to examine whether arithmetic or geometric means offer the best estimate of efficacy in a situation where the true efficacy is known.
Besier, R.B.   +3 more
core  

Digital image contrast assessment based on the Weibull distribution parameters

open access: yesСистемный анализ и прикладная информатика, 2021
The goal of the studies described in the paper is to find a quantitative assessment that maximally correlates with the subjective assessment of the contrast image quality in the absence of reference image.
Y. I. Golub, F. V. Starovoitov
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

On two derivative sequences from scaled geometric mean sequence terms. [PDF]

open access: yes, 2018
The so called geometric mean sequence recurrence, with additional scaling variable, produces a sequence for which the general term has a known closed form. Two types of derivative sequence—comprising products of such sequence terms—are examined.
Rabago, Julius, F. T.   +2 more
core  

On approximating the quasi-arithmetic mean

open access: yesJournal of Inequalities and Applications, 2019
In this article, we prove that the double inequalities α1[7C(a,b)16+9H(a,b)16]+(1−α1)[3A(a,b)4+G(a,b)4]
Tie-Hong Zhao   +3 more
doaj   +1 more source

The Geometrization of Meaning

open access: yes, 2021
One of the greatest problems in philosophy is that of meaning. The turning point in thinking on meaning was Tarski's definition of truth, and the rapid development of logical semantics and model theory was a consequence of this achievement. Perhaps less well-known among classical logicians and philosophers is that it is category theory that provides ...
openaire   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Clustering Signed Networks with the Geometric Mean of Laplacians [PDF]

open access: yes, 2016
Signed networks allow to model positive and negative relationships. We analyze existing extensions of spectral clustering to signed networks. It turns out that existing approaches do not recover the ground truth clustering in several situations where ...
Hein, Matthias   +2 more
core  

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