Results 71 to 80 of about 63,827 (265)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Modeling, validation and verification of three-dimensional cell-scaffold contacts from terabyte-sized images

BMC Bioinformatics, 2017
Background Cell-scaffold contact measurements are derived from pairs of co-registered volumetric fluorescent confocal laser scanning microscopy (CLSM) images (z-stacks) of stained cells and three types of scaffolds (i.e., spun coat, large microfiber, and
Peter Bajcsy, Soweon Yoon, Stephen J. Florczyk, Nathan A. Hotaling, Mylene Simon, Piotr M. Szczypinski, Nicholas J. Schaub, Carl G. Simon, Mary Brady, Ram D. Sriram   +9 more
doaj   +1 more source

Multi-objective optimization and comparison of surrogate models for separation performances of cyclone separator based on CFD, RSM, GMDH-neural network, back propagation-ANN and genetic algorithm

Engineering Applications of Computational Fluid Mechanics, 2020
Pressure drop (Δp) and collection efficiency (η) are used to evaluate the separation performance of the cyclone separator. In this study, we conducted comparative study of cyclone models using response surface methodology (RSM), back propagation neural ...
Donggeun Park, Jemyung Cha, Moonjeong Kim, Jeung Sang Go   +3 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

A fast gamma-ray dose rate assessment method for complex geometries based on stylized model reconstruction

Nuclear Engineering and Technology, 2019
A fast gamma-ray dose rate assessment method for complex geometries based on stylized model reconstruction and point-kernel method is proposed in this paper.
Li-qun Yang, Yong-kuo Liu, Min-jun Peng, Meng-kun Li, Nan Chao   +4 more
doaj   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Layered manufacturing for medical imaging data

Advances in Mechanical Engineering, 2019
Layered manufacturing techniques have been successfully employed to construct scanned objects from three-dimensional medical image data sets. The printed physical models are useful tools for anatomical exploration, surgical planning, teaching, and ...
Shyh-Kuang Ueng, Hsin-Cheng Huang, Chieh-Shih Chou, Hsuan-Kai Huang   +3 more
doaj   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Geometrical Variation’s Influence on the Effects of Stimulation May be Important in the Conventional and Multi-Array tDCS–Comparison of Electrical Fields Computed

IEEE Access, 2019
Transcranial direct current stimulation (tDCS) is an emerging non-invasive neuromodulation method that is convenient and popular for clinical use. However, there is a practical issue when tDCS is applied to actual subjects, in which the geometrical ...
Cheolki Im, Hyeon Seo, Sung Chan Jun
doaj   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source