Results 61 to 70 of about 479,657 (292)

Identification of geometrical models of interface evolution for dendritic crystal growth [PDF]

open access: yes, 2010
This paper introduces a method for identifying geometrical models of interface evolution, directly from experimental imaging data. These local growth models relate normal growth velocity to curvature and its derivatives estimated along the growing ...
Billings, S.A.   +4 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Fractal frontiers of bursts and cracks in a fiber bundle model of creep rupture

open access: yes, 2015
We investigate the geometrical structure of breaking bursts generated during the creep rupture of heterogeneous materials. Based on a fiber bundle model with localized load sharing we show that bursts are compact geometrical objects, however, their ...
Danku, Zsuzsa   +2 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

CFD-model of the mass transfer in the vertical settler

open access: yesNauka ta progres transportu, 2013
Purpose. Nowadays the mathematical models of the secondary settlers are intensively developed. As a rule the engineers use the 0-D models or 1-D models to design settlers.
E. K. Nagornaya
doaj  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Geometrical four-point functions in the two-dimensional critical Q-state Potts model: connections with the RSOS models

open access: yesJournal of High Energy Physics, 2020
The “bootstrap determination” of the geometrical correlation functions in the two-dimensional Potts model proposed in a paper by Picco et al. [1] was later shown in [2] to be incorrect, the actual spectrum of the model being considerably more complex ...
Yifei He   +3 more
doaj   +1 more source

From Logical to Distributional Models [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2014
The paper relates two variants of semantic models for natural language, logical functional models and compositional distributional vector space models, by transferring the logic and reasoning from the logical to the distributional models.
Anne Preller
doaj   +1 more source

From Liquid Structure to Configurational Entropy: Introducing Structural Covariance

open access: yes, 2016
We connect the configurational entropy of a liquid to the geometrical properties of its local energy landscape, using a high-temperature expansion. It is proposed that correlations between local structures arises from their overlap and, being geometrical
Harrowell, Peter, Ronceray, Pierre
core   +2 more sources

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