Results 71 to 80 of about 1,454 (181)

Gepants for headache prevention in children and adolescents: A multicenter chart review study. [PDF]

Headache
Abstract Introduction There is an unmet need for safe, evidence‐based pharmacologic treatments for migraine prevention in children and adolescents. Rimegepant and atogepant, calcitonin gene‐related peptide receptor antagonists (gepants), have been shown to be efficacious and well‐tolerated ...
Shin L, Mentz O, Gelfand AA, de Prado BM, Shapiro H, Oh A, Onifade OO, Saunders J, Raj N, Szperka CL.   +9 more
europepmc   +4 more sources

Is the right way to go in between?

The Journal of Headache and Pain, 2023
In the study by Johnston et al., gepants were meant to be taken to treat emergent migraine. It is tempting to speculate what the effect would be if patients were instructed to take a gepant as needed (PRN) or even prior to headache onset.
Andreas R. Gantenbein, Andreas Kleinschmidt   +1 more
doaj   +1 more source

CGRP Antagonism and Ketogenic Diet in the Treatment of Migraine

Medicina
The study of migraine is based on the complexity of the pathology, both at the pathophysiological and epidemiological levels. Although it affects more than a billion people worldwide, it is often underestimated and underreported by patients.
Francesca Finelli, Alessia Catalano, Michele De Lisa, Giuseppe Andrea Ferraro, Sabino Genovese, Federica Giuzio, Rosanna Salvia, Carmen Scieuzo, Maria Stefania Sinicropi, Fabiano Svolacchia, Antonio Vassallo, Alessandro Santarsiere, Carmela Saturnino   +12 more
doaj   +1 more source

Lidocaine Combined With Platelet‐Rich Plasma for Stellate Ganglion Block in Chronic Migraine: A Multicenter, Prospective, Propensity Score‐Matched Cohort Study

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Objectives To explore the association of stellate ganglion block with platelet‐rich plasma plus lidocaine with clinical outcomes in adults with chronic migraine, in comparison to lidocaine alone. Methods This multicenter prospective exploratory study enrolled 200 adults with chronic migraine scheduled for stellate ganglion block across three ...
Lu Liu, Baolin Duan, Tao Ma, Long Li, Dong Yang, Fang Luo   +5 more
wiley   +1 more source

Migraine and Work‐Disability: New Treatments Reduce Work‐Related Burden Among Migraine Population

European Journal of Neurology, Volume 33, Issue 9, September 2026.
Migraine is a disabling disease with a substantial hidden work‐related burden, often underestimated by standard patient‐reported outcome measures. In this study, patients treated with anti‐CGRP monoclonal antibodies showed a reduction in monthly migraine days and acute medication use, together with an improvement in work‐related burden as measured by ...
Danilo Antonio Montisano, Gloria Vaghi, Claudia Altamura, Alessandra Parisi, Roberto De Icco, Marilena Marcosano, Alessia Marcassoli, Erika Guastafierro, Michele Corrado, Domenico D'Amico, Grazia Sances, Fabrizio Vernieri, Cristina Tassorelli, Alberto Raggi, Licia Grazzi   +14 more
wiley   +1 more source

Relative efficacy of lasmiditan versus rimegepant and ubrogepant as acute treatments for migraine: network meta-analysis findings

The Journal of Headache and Pain, 2022
Background In the absence of head-to-head trials, comprehensive evidence comparing onset of efficacy of novel agents for acute treatment of migraine is lacking.
Pepa Polavieja, Mark Belger, Shiva Kumar Venkata, Stefan Wilhelm, Erin Johansson   +4 more
doaj   +1 more source

Online interest in calcitonin gene‐related peptide‐therapies: An infodemiology study using Google trends

Headache: The Journal of Head and Face Pain, Volume 66, Issue 8, Page 1788-1800, September 2026.
Abstract Objective To evaluate changes in public interest in calcitonin gene‐related peptide therapies associated with major product lifecycle milestones using online search data from the United States and Europe. Background Calcitonin gene‐related peptide therapies have transformed migraine treatment, but the impact of key product lifecycle milestones
Bradley Ong, Jad El Ahdab, Nicolas Thompson, Maithili Bhagat, John Ney, Allison L. Weathers   +5 more
wiley   +1 more source

Calcitonin gene-related peptide in migraine: from pathophysiology to treatment.

, 2021
20.500.12530/87853It has been observed in recent years that levels of such molecules as calcitonin gene-related peptide (CGRP) and, to a lesser extent, the pituitary adenylate cyclase-activating peptide are elevated during migraine attacks and in chronic
Santos-Lasaosa, S, Cuadrado, M L, Huerta, M, Latorre, G, Díaz-Insa, S, Gago-Veiga, A, Pozo-Rosich, P, Láinez, J M, Leira, R, Belvís, R, Porta-Etessam, J, Pascual, J, Irimia, P, Sánchez Del Río, M, Guerrero-Peral, A L, Viguera, J   +15 more
core   +1 more source

Weight loss with atogepant in the long‐term treatment of migraine: An interim analysis of a safety endpoint from a phase 3, multicenter, open‐label, 156‐week extension study

Headache: The Journal of Head and Face Pain, Volume 66, Issue 8, Page 1730-1740, September 2026.
Abstract Objective To assess weight loss with atogepant 60 mg once daily during long‐term treatment of chronic migraine (CM) and episodic migraine (EM) among participants previously failed by two to four classes of conventional oral preventive medications.
Dale S. Bond, Jonathan H. Smith, Alexandra Sinclair, Peter J. Goadsby, Jessica Ailani, Yingyi Liu, Rosa De Abreu Ferreira, Brett Dabruzzo, Joel M. Trugman, B. Lee Peterlin   +9 more
wiley   +1 more source

Mechanisms of Acupuncture on the Neurovascular Unit in Migraine: A Narrative Review

European Journal of Neurology, Volume 33, Issue 8, August 2026.
ABSTRACT Objective The neurovascular unit (NVU) is a core structural and functional entity involved in migraine pathogenesis. Acupuncture may exert therapeutic effects by protecting NVU integrity. This narrative review aims to summarize the current evidence on the mechanisms by which acupuncture protects the NVU in migraine.
Yajie Wang, Chao Zhang, Linbo Shen, Yuanyuan Wang, Xiaocheng Wang, Linjing Song, Li Wang, Ningle Zhang, Dayong Ma, Tao Xiong   +9 more
wiley   +1 more source