Results 91 to 100 of about 323,912 (312)

New horizons in geriatric medicine education and training: The Need for pan-European education and training standards

, 2017
The ageing population ought to be celebrated as evidence for the efficacy of modern medicine, but the challenge that this demographic shift presents for 21st century healthcare systems, with increasing numbers of people living with multi-morbidity and ...
Masud, T, Veninsek, G, Gordon, A, Frühwald, T, Stuck, Andreas, Bako, G, Van Den Noortgate, NJ, Jonsdottir, AB, Ihle-Hansen, HB, Pinter, GF, Fisher, JM, Blain, H, Roller-Wirnsberger, RE, Martinez-Velilla, N, Singler, K, Knight, P, Vassallo, MA, Petermans, J, Blundell, A, Lambert, M, Holm, EA, Davidovic, MM, Kolk, H, Nuotio, MS, Krulder, JWM, Thompson, S, Burns, E, Maggi, S   +27 more
core   +1 more source

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

eHealth in geriatric rehabilitation: an international consensus study [PDF]

Consensus; Geriatric rehabilitation; eHealthConsenso; Rehabilitación geriátrica; eSaludConsens; Rehabilitació geriàtrica; eSalutPurpose: Current evidence on the use of eHealth in geriatric rehabilitation is limited.
Choukou, Mohamed-Amine, Persoon, Anke, Kraaijkamp, Jules, Achterberg, Wilco, Chavannes, Niels H., Dockery, Frances, Pérez, Laura Mónica   +6 more
core   +1 more source

Freestanding Hierarchical‐Porous BCZT Thin Films Enable Efficient Ultrasonic Energy Harvesting in Soft Tissue

Advanced Science, EarlyView.
Freestanding hierarchical‐porous BCZT thin films integrate a compliant porous surface with a dense piezoceramic backbone to balance mechanical reliability, voltage sensitivity, and acoustic coupling. The films enable stable wearable pulse‐wave monitoring and enhanced tissue‐coupled ultrasonic energy harvesting, offering a promising route toward soft ...
Zifan Li, Shengwei Gao, Wang Hong, Yuxin Chen, Yiyang Gu, Xu Wang, Chen Tang, Ying Hong, Xuemu Li, Xiaodong Yan, Yi Zheng, Yiming Liu, Junchen Liao, Biao Wang, Shiyuan Liu   +14 more
wiley   +1 more source

Anogenital Warts in Geriatrics: Immunosenescence and New Sexual Contacts? A Case Report

Clinical, Cosmetic and Investigational Dermatology
Pati Aji Achdiat,1 Dini Atiyah,1 Fitri Yulianti,1 Endang Sutedja,1 Srie Prihianti Gondokaryono,1 Hermin Aminah Usman,2 Retno Hesty Maharani1 1Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran – Dr.
Achdiat PA, Atiyah D, Yulianti F, Sutedja E, Gondokaryono SP, Usman HA, Maharani RH   +6 more
doaj  

The geriatric canon

Monaldi Archives for Chest Disease, 2019
Over the years Geriatrics and gerontology have developed a language shared by most clinicians and researchers who unequivocally defines the health conditions of aging people: one could speak of "geriatric canon", i.e. the set of fundamentals (paradigms, principles, standard reference vocabulary) of geriatric knowledge, the heritage from which they draw
openaire   +4 more sources

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Pre-surgical Geriatric Syndromes, Frailty, and Risks for Postoperative Delirium in Older Patients Undergoing Gastrointestinal Surgery: Prevalence and Red Flags

, 2017
We sought to identify and evaluate red flags for pre-surgical geriatric conditions (geriatric syndromes, frailty, and risks for postoperative delirium) in older patients undergoing gastrointestinal surgery.
嚴崇仁;林明燦;陳佳慧;梁金銅, Chen, Cheryl Chia-Hui;Lin, Ming-Tsan;Liang, Jin-Tung;Chen, Chun-Min;Yen, Chung-Jen;Huang, Guan-Hua   +1 more
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A European Research Agenda for Geriatric Emergency Medicine: a modified Delphi study

, 2020
Key Summary PointsAim To provide an inventory and prioritisation of research questions amongst GEM professionals throughout Europe. Findings A list of 10 research questions was identified and prioritised.
Mooijaart, S.P. and Nickel, C.H. and Conroy, S.P. and Lucke, J.A. and van Tol, L.S. and Olthof, M. and Blomaard, L.C. and Buurman, B.M. and Dundar, Z.D. and de Groot, B. and Gasperini, B. and Heeren, P. and Karamercan, M.A. and McNamara, R. and Mitchell, A. and van Oppen, J.D. and Martin Sanchez, F.J. and Schoon, Y. and Singler, K. and Spode, R. and Skúldóttir, S. and Thorrsteindottir, T. and van der Velde, M. and Wallace, J., Mooijaart, Simon P. and Nickel, Christian H. and Conroy, Simon P. and Lucke, Jacinta A. and van Tol, Lisa S. and Olthof, Mareline and Blomaard, Laura C. and Buurman, Bianca M. and Dundar, Zerrin D. and de Groot, Bas and Gasperini, Beatrice and Heeren, Pieter and Karamercan, Mehmet A. and McNamara, Rosa and Mitchell, Aine and van Oppen, James D. and Sanchez, F. Javier Martin and Schoon, Yvonne and Singler, Katrin and Spode, Renan and Skuldottir, Sigrun and Thorrsteindottir, Thordis and van der Velde, Marije and Wallace, James   +1 more
core   +1 more source