Results 121 to 130 of about 6,868,011 (264)

In-hospital falls among geriatric patients: prevalence of major injuries and associated factors

BMC Geriatrics
Background Hospital falls can cause major injuries such as fractures or brain injuries. This study aimed to investigate the prevalence of major injuries and associated factors in geriatric patients who sustained in-hospital falls and to compare them with
Yangjin Jegal, Chae-Chil Lee, Young Dae Jeon, Sang-Heon Oh, Soe Hee Ahn, Ki-Bong Park   +5 more
doaj   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Features of geriatric patients in psychiatric consultation: a retrospective comparative study [PDF]

Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2010
Objective: The proportion of geriatric inpatients has increased with the increase of the elderly in the general population. This study aims to compare the medical and psychiatric conditions of geriatric inpatients with those of non-geriatric adult ...
İ. Çağrı Yazgan, Nurhan Fıstıkçı, M. Kemal Kuşçu, Aylan Gımzal Gönentür, Volkan Topçuoğlu, Ali Keyvan   +5 more
doaj  

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Cognitive impairment in geriatric chronic schizophrenic patients: a cross‐national study in New York and London

, 1997
Severe cognitive impairment has been reported in large numbers of geriatric chronic schizophrenic patients in the US, with this impairment also being related to severe negative symptoms and adaptive deficits. It is not clear if this impairment is related
Leff, Julian, Harvey, Philip D, Davidson, Michael, Anderson, Jeremy, Trieman, Noam   +4 more
core   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

Advanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang, Pan Liu, Jie Lei, Shuchang Peng, Qiu Chen, Wei Guan, Yizhou Zhu, Gang Liu, Xiaobo Feng, Cao Yang, Lei Tan   +10 more
wiley   +1 more source

Anatomical Changes After Stabilisation Splint Therapy: A Systematic Review and Meta-analysis

International Dental Journal
Introduction: Stabilisation splint therapy (SST) is one of the treatment options for patients with temporomandibular disorder (TMD) and has strong evidence supporting its benefits.
Ronlada Porntirit, Paak Rewthamrongsris, Itt Assoratgoon, Thanaphum Osathanon   +3 more
doaj   +1 more source

Identifying Delirium in the Geriatric Population

, 2023
Delirium is a severe change in brain function that can have short and long-term consequences for the hospitalized geriatric patient. Untreated delirium can lead to increased lengths of stay, falls, reduced function post-discharge, and even increased ...
NC DOCKS at East Carolina University, Gee, Amy   +1 more
core  

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

Advanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen, Xin Liu, Gaoran Ge, Li Xu, Ziyu Zhang, Chang Lv, Hao Xu, Wenhao Li, Yi Qin, Qifeng Sheng, Qihan Wang, Hongxia Li, Jun Zhou, Huilin Yang, Dechun Geng   +14 more
wiley   +1 more source

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source