Results 101 to 110 of about 285,516 (355)

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

open access: yesAdvanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang   +12 more
wiley   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Visible Light‐Activated ZnO@CuO Coaxial Nanofibers Enhance Infected Skin Wound Healing Through Construction of p‐n Heterojunctions

open access: yesAdvanced Science, EarlyView.
Coaxial ZnO@CuO nanofibers activated by visible light generate ROS through enhanced photocatalytic reactions driven by improved electron hole separation in the heterojunction. This strategy enables rapid antimicrobial activity and early infection control, thereby promoting the healing of MRSA infected and diabetic wounds with biosafe and easily ...
Pengrui Dang   +11 more
wiley   +1 more source

Comparing Iranian and Duke University\'s Master of Nursing Education Programs in Geriatrics: A Comparative Study [PDF]

open access: yesPizhūhish dar Āmūzish-i ̒ulūm-i Pizishkī
Introduction: To identify the strengths and weaknesses of the curriculum and improve the quality of education in the Master of Nursing in Geriatrics, this study aimed to compare the educational program of the Master of Nursing in Geriatrics at Golestan ...
Hamideh Mancheri   +3 more
doaj  

"Without racism there would be no geriatrics": South Asian overseas-trained doctors and the development of Geriatric Medicine in the United Kingdom', 1950-2000

open access: yes, 2016
The long history of medical migration to the united Kingdom is relatively well known. however, until recently the story of the contribu-tion of South Asian doctors to specific fields has been less discussed.
Bornat, Joanna   +2 more
core  

National Blueprint: Increasing Physical Activity Among Adults Age 50 and Older [PDF]

open access: yes, 2001
Outlines a variety of approaches for organizations, associations, and agencies to plan strategies to help people age 50 and older increase their physical ...

core  

Integrating Neuropsychology into Interprofessional Geriatrics Clinics [PDF]

open access: bronze, 2021
Amanda Brunette   +7 more
openalex   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

open access: yesAdvanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan   +19 more
wiley   +1 more source

An Initial Study on the Ethical and Moral Standards of Geriatrics Clinical Instructors Construction

open access: yesGuoji laonian yixue zazhi
Objective With the accelerating aging of the global population, the geriatrics has garnered significant attention in recent years. Geriatrics clinical specialty medical students represent a crucial talent pool for this field.
Xu ying, Tao Xinyu, Chen Sen, Qu Chen
doaj   +1 more source

Care Management of Patients With Complex Health Care Needs [PDF]

open access: yes, 2009
Explores how patients' complexity of healthcare needs, vulnerability, and age affect the cost and quality of their health care. Examines the potential for care management to improve quality of care and reduce costs, elements of success, and ...
Rachel Berry-Millett, Thomas Bodenheimer
core  

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