Results 111 to 120 of about 285,790 (386)

ESPEN practical guideline: Clinical nutrition and hydration in geriatrics.

Clinical Nutrition, 2022
D. Volkert, A. Beck, T. Cederholm, A. Cruz-Jentoft, L. Hooper, E. Kiesswetter, M. Maggio, A. Raynaud-Simon, C. Sieber, L. Sobotka, D. V. van Asselt, R. Wirth, S. Bischoff   +12 more
semanticscholar   +1 more source

Visiting Nurse Services of Newport and Bristol County: Increasing Program Awareness for the Help at Home Program [PDF]

, 2014
We came up with the idea of using a cost analysis to clearly demonstrate the advantage of home care vs. hospitalization. John Hopkins Bay view Medical Center conducted a study within their geriatrics unit to test their Hospital At Home program against ...
Cooper, Joel, Fedora, Monique, Nash, Kevin, Nessa, Jon, Robinson, Arnold, Villeneuve, Nick   +5 more
core   +1 more source

Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu, Zhihuang Zheng, Marleen Silke Oswald, Guozhe Cheng, Jun Liu, Qidi Zhai, Ute Kruegel, Michael Schaefer, Holger Gerhardt, Nicole Endlich, Maik Gollasch, Stefan Simm, Dmitry Tsvetkov   +12 more
wiley   +1 more source

Reduced level of arousal and increased mortality in adult acute medical admissions: a systematic review and meta-analysis [PDF]

, 2017
Background Reduced level of arousal is commonly observed in medical admissions and may predict in-hospital mortality. Delirium and reduced level of arousal are closely related.
A Calle, A Liberati, A Nicolini, AE Jones, Alasdair M. J. MacLullich, American College of Surgeons Committee on Trauma, Amy Todd, BJ Naughton, BO Onadeko, C Barfod, C Chih-Hsun, CF Otieno, CN Sessler, David J. Stott, DJ Meagher, DK Kiely, E Francia, E Kaya, E. Wesley Ely, European Delirium Association and American Delirium Society, F Delahaye, G Bellelli, G Bellelli, G Teasdale, HA Conte, J Witlox, Jennifer K. Burton, JH Han, K Neufeld, K Oedorf, K Rockwood, MA Aslaner, ME Mikkelsen, MR Navinan, O Kruse, P Dutta, PK Myint, Review Manager (RevMan) [Computer program], RW Duckitt, S Rathour, S Zweig, Samantha Blackley, SK Inouye, Susan D. Shenkin, SY Kim, TA Jackson, TM Merz, VC Burch, W Hasegawa, Y Sakamoto, Y Yamauchi, Z Tieges, Zoë Tieges   +52 more
core   +4 more sources

Targeting IGF1R Overcomes Armored and Cold Tumor Microenvironment and Boosts Immune Checkpoint Blockade in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
IGF1R is highly expressed in the armored & cold tumors, and collagen mediates IGF1R at the transcriptional and post‐translational levels to promote TNBC cell invasion and immune escape and to stabilize its own structure by interacting with the collagen receptor DDR1.
Mengyun Wan, Jie Mei, Yun Cai, Ji Zhou, Ningyi Xue, Ying Jiang, Yan Zhang, Jingjing Huang, Yichao Zhu   +8 more
wiley   +1 more source

Preparing Family Caregivers to Recognize Delirium Symptoms in Older Adults After Elective Hip or Knee Arthroplasty [PDF]

, 2017
Objectives To test the feasibility of a telephone-based intervention that prepares family caregivers to recognize delirium symptoms and how to communicate their observations to healthcare providers.
Boaz, Lesley, Bull, Margaret J., Gettrust, Lynn, Greene, Maureen T., Hagle, Mary E., Holmes, Sue Baird, Maadooliat, Mehdi, Saczynski, Jane S.   +7 more
core   +1 more source

Cross-sectional associations between personality traits and device-based measures of step count and sedentary behaviour in older age: the Lothian birth cohort 1936 [PDF]

, 2019
BACKGROUND: While the associations between personality traits and self-reported physical activity are well replicated, few studies have examined the associations between personality and device-based measures of both physical activity and sedentary ...
,, Chastin, Sebastien, Dall, Philippa M., Deary, Ian, Dontje, Manon, Gale, Catharine, Skelton, Dawn A., Čukić, Iva   +7 more
core   +4 more sources

Pinosylvin Inhibits Inflammatory and Osteoclastogenesis via NLRP3 Inflammasome

Advanced Science, EarlyView.
Pinosylvin blocks LPS and RANKL induced NEK7/NLRP3 interaction, inhibiting NLRP3 inflammasome oligomerization and assembly, reducing IL‐1β maturation and GSDMD cleavage, and improving the inflammatory microenvironment and abnormal osteoclastogenesis. Abstract Pro‐inflammatory cytokines such as TNF, IL‐1, and IL‐6 trigger aberrant osteoclastogenesis and
Wei Zhang, Xiangbing Wu, Wenming Li, Haifeng Zhang, Yijun Wang, Jing Xu, Wenhao Li, Yi Qin, Zebin Wu, Gaoran Ge, Shujun Lv, Lu Mao, Liangliang Wang, Dechun Geng   +13 more
wiley   +1 more source

[Sabbatical Report] [PDF]

, 2014
Write, submit and present information on ...
Bradley, Dana Burr
core   +1 more source

The role of concern about falling on stepping performance during complex activities [PDF]

, 2019
Background There is limited understanding of the underlying mechanisms explaining the role of concern about falling on fall risk in older people. Anxiety is known to interact with cognitive resources and, as people get older, they require more cognitive ...
Brodaty, Henry, Close, Jacqueline C. T., Crombez, Geert, Delbaere, Kim, Lord, Stephen R., Sachdev, Perminder, Viaje, Shaira   +6 more
core   +1 more source