Results 11 to 20 of about 11,144,846 (357)

Treatment of Germ Cell Testicular Cancer

open access: yesActa Clinica Croatica, 2020
Germ-cell testicular cancer (GCTC) is a malignant neoplasm derived from the primordial germ cell. Although it accounts for approximately 1% of all malignancies in men, it is the most common cancer of younger male population, with the highest incidence ...
Ana Koši Kunac   +3 more
doaj   +1 more source

Surgical treatment of metastatic germ cell cancer

open access: yesAsian Journal of Urology, 2021
Among young men between the ages of 15 and 40 years, germ cell cancer is the most common solid tumor [1]. The worldwide incidence of germ cell cancer is 70 000 cases.
Andreas Hiester, Peter Albers
doaj   +1 more source

Germ cell markers in fishes - A review

open access: yesAquaculture and Fisheries, 2022
Identification of germ cell markers in fishes is crucial to track the germ cell differentiation and migration for manipulation of the cells to study sexual differentiation as well as to carry out transgenic transplantation techniques.
Sultana Begum   +3 more
doaj   +1 more source

Strategies for Mammalian Mesenchymal Stem Cells Differentiation into Primordial Germ Cell-Like Cells: A Review [PDF]

open access: yesCell Journal, 2022
Primordial germ cells develop into oocytes and sperm cells. These cells are useful resources in reproductive biology and regenerative medicine. The mesenchymal stem cells (MSCs) have been examined for in vitro production of primordial germ cell-like ...
Shabnam Fayezi   +3 more
doaj   +1 more source

Zebrafish as a Model for Germ Cell Regeneration

open access: yesFrontiers in Cell and Developmental Biology, 2021
Germ cell acts as a link between transfer of genetic information and process of species evolution. Defects or malformations of germ cells can lead to infertility or tumors.
Zigang Cao, Qifen Yang, Lingfei Luo
doaj   +1 more source

Functional analysis of the Drosophila embryonic germ cell transcriptome by RNA interference. [PDF]

open access: yesPLoS ONE, 2014
In Drosophila melanogaster, primordial germ cells are specified at the posterior pole of the very early embryo. This process is regulated by the posterior localized germ plasm that contains a large number of RNAs of maternal origin.
Ferenc Jankovics   +6 more
doaj   +1 more source

Tracing the cellular basis of islet specification in mouse pancreas

open access: yesNature Communications, 2020
The cellular basis of islet morphogenesis and fate allocation remain unclear. Here, the authors use a R26-CreER-R26R-Confetti mouse line to follow quantitatively the clonal dynamics of islet formation showing how, during the secondary transition, islet ...
Magdalena K. Sznurkowska   +7 more
doaj   +1 more source

Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]

open access: yes, 2010
Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H.   +4 more
core   +2 more sources

Germ cells [PDF]

open access: yesCurrent Opinion in Genetics & Development, 1999
Recently, cell signaling has been shown to be required for the formation of germ cells in the mouse embryo, direct observation of germ cell migration in living mouse embryos has been achieved, novel genes that control germ-cell migration have been identified in Drosophila, and the roles of many components of germ plasm in several species have become ...
openaire   +3 more sources

Rare Intracranial Multifocal Non-Germinomatous Germ Cell Tumor in an 18-Year-Old Male: A Case Report

open access: yesActa Clinica Croatica, 2023
Intracranial germ cell tumors are rare brain tumors that are distinguished based on their histology and selected tumor markers. Non-germinomatous germ cell tumors are a diverse group of such tumors having the poorest prognosis.
Nikolina Sesar   +3 more
doaj   +1 more source

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