Results 11 to 20 of about 448,010 (312)
Functional analysis of the Drosophila embryonic germ cell transcriptome by RNA interference. [PDF]
In Drosophila melanogaster, primordial germ cells are specified at the posterior pole of the very early embryo. This process is regulated by the posterior localized germ plasm that contains a large number of RNAs of maternal origin.
Ferenc Jankovics +6 more
doaj +6 more sources
Evidence against a germ plasm in the milkweed bug Oncopeltus fasciatus, a hemimetabolous insect [PDF]
Summary Primordial germ cell (PGC) formation in holometabolous insects like Drosophila melanogaster relies on maternally synthesised germ cell determinants that are asymmetrically localised to the oocyte posterior cortex.
Ben Ewen-Campen +2 more
doaj +6 more sources
The germline of Caenorhabditis elegans derives from a single founder cell, the germline blastomere P(4). P(4) is the product of four asymmetric cleavages that divide the zygote into distinct somatic and germline (P) lineages. P(4) inherits a specialized cytoplasm ("germ plasm") containing maternally encoded proteins and RNAs.
Jennifer T, Wang, Geraldine, Seydoux
openaire +2 more sources
Tracing the cellular basis of islet specification in mouse pancreas
The cellular basis of islet morphogenesis and fate allocation remain unclear. Here, the authors use a R26-CreER-R26R-Confetti mouse line to follow quantitatively the clonal dynamics of islet formation showing how, during the secondary transition, islet ...
Magdalena K. Sznurkowska +7 more
doaj +1 more source
Recently, cell signaling has been shown to be required for the formation of germ cells in the mouse embryo, direct observation of germ cell migration in living mouse embryos has been achieved, novel genes that control germ-cell migration have been identified in Drosophila, and the roles of many components of germ plasm in several species have become ...
openaire +3 more sources
Migration of germline progenitor cells is directed by sphingosine-1-phosphate signalling in a basal chordate. [PDF]
The colonial ascidian Botryllus schlosseri continuously regenerates entire bodies in an asexual budding process. The germ line of the newly developing bodies is derived from migrating germ cell precursors, but the signals governing this homing process ...
Bui, Connor +4 more
core +1 more source
Rare Intracranial Multifocal Non-Germinomatous Germ Cell Tumor in an 18-Year-Old Male: A Case Report
Intracranial germ cell tumors are rare brain tumors that are distinguished based on their histology and selected tumor markers. Non-germinomatous germ cell tumors are a diverse group of such tumors having the poorest prognosis.
Nikolina Sesar +3 more
doaj +1 more source
Identification of side population cells in mouse primordial germ cells and prenatal testis [PDF]
In mammals, the stem cells of spermatogenesis are derived from an embryonic cell population called primordial germ cells (PGCs). Spermatogonial stem cells displaying the "side population" (SP) phenotype have been identified in the immature and adult ...
De Felici, Massimo +6 more
core +2 more sources
Cell cycle regulation for meiosis in mammalian germ cells
In mouse fetal gonads, germ cell development is accompanied by changes in cell cycle mode in response to external signals and intrinsic mechanisms of cells.
Ryuki SHIMADA, Kei-ichiro ISHIGURO
doaj +1 more source
Role of β-catenin in post-meiotic male germ cell differentiation. [PDF]
Though roles of β-catenin signaling during testis development have been well established, relatively little is known about its role in postnatal testicular physiology.
Yao-Fu Chang +4 more
doaj +1 more source

